Maternal-prenatal gut microbiome-systemic metabolome perturbations and TH2-skewed immunity link to offspring gut microbiome disruption and atopic dermatitis susceptibility [0.03%]
母体-胎儿肠道菌群-系统代谢组紊乱及TH2偏移的免疫反应与子代肠道菌群失调和特应性皮炎易感性的关联研究
Daniel Zhi Wei Ng,Gaik Chin Yap,Carina Jing Xuan Tay et al.
Daniel Zhi Wei Ng et al.
Single-cell omics data-driven decoding of tumor clonal evolution through reinforcement learning [0.03%]
基于单细胞组学数据的肿瘤克隆进化解码的强化学习方法
Qiushun He,Zhilong Zhang,Yuanmei Wang et al.
Qiushun He et al.
Spatial transcriptomics reveals a molecular tumor budding signature in head and neck cancer [0.03%]
空间转录组学揭示了头颈部癌症中分子肿瘤芽出特征签名
Iordanis Ourailidis,Markus Ball,Vanessa Vogel et al.
Iordanis Ourailidis et al.
Background: Tumor budding (TB) is a histopathological feature associated with poor prognosis across multiple cancer types, including head and neck squamous cell carcinoma (HNSCC). Tumor buds represent the earliest traceab...
SpaPheno: linking spatial transcriptomics to clinical phenotypes with interpretable machine learning [0.03%]
SpaPheno：使用可解释机器学习将空间转录组学与临床表型联系起来
Bin Duan,Xiaojie Cheng,Hua Zou
Bin Duan
Longitudinal cell-free DNA methylome and fragmentome profiles in health uncover signatures of cell type and demographic origin [0.03%]
纵向无细胞DNA甲基化组和片段组谱系在健康中揭示了细胞类型和人口来源的特征
Mio Aerden,Tatjana Jatsenko,Kaat Leroy et al.
Mio Aerden et al.
Co-occurrence of transcriptionally distinct persister cell states underpins neoadjuvant therapy resistance in triple‑negative breast cancer [0.03%]
三阴性乳腺癌新辅助治疗耐药的转录上不同的休眠细胞状态共存机制
Yu Zhang,Fatemeh Ahmadi Moughari,Ioanna Mavrommati et al.
Yu Zhang et al.
Identification of an episignature for CHD3-related Snijders Blok-Campeau syndrome reveals heterogeneity in the CHARGE syndrome episignature: towards a better characterisation of chromatinopathies [0.03%]
CHD3相关Snijders-Blok-Campeau综合征的表观标志鉴定揭示了CHARGE综合症表观特征的异质性：更好地表征染色质紊乱综合征
Amandine Santini,Angelo Tognon,Anne-Claire Richard et al.
Amandine Santini et al.
Background: Recent advances in sequencing technologies have enhanced patient diagnosis; however, causal pathogenic variants remain unidentified for a significant number of patients due to limited understanding of certain ...
Attention-based deep learning for analysis of pathology images and gene expression data in lung squamous premalignant lesions [0.03%]
基于注意力的深度学习在肺鳞状上皮癌前病变病理图像和基因表达数据分析中的应用
Lingyi Xu,Yohana Kefella,Yichi Zhang et al.
Lingyi Xu et al.
Single cell multiomics revealed fibrotic trajectories of endometrial cells and interaction with the pro-fibrotic macrophages in intrauterine adhesion [0.03%]
单细胞多组学揭示了宫腔粘连子宫内膜纤维化的进程及促纤维化巨噬细胞的相互作用
Yu Li,Wei Wu,Houyi Lv et al.
Yu Li et al.
Alignment of spatial transcriptomics slices across diseases, platforms and conditions [0.03%]
跨疾病、平台和条件的空间转录组切片对齐
Yu Wang,Zaiyi Liu,Qingchen Zang et al.
Yu Wang et al.