Correction: Artificial intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine [0.03%]
订正:癌症表观遗传学中的人工智能:泛癌检测和精准医学进展的综述
Karishma Sahoo,Prakash Lingasamy,Masuma Khatun et al.
Karishma Sahoo et al.
Published Erratum
Epigenetics & chromatin. 2025 Jul 11;18(1):42. DOI:10.1186/s13072-025-00604-7 2025
Molecular mechanisms and biological functions of active DNA demethylation in plants [0.03%]
植物主动DNA去甲基化的分子机制及其生物学功能
Ruixian Zhu,Yan Xue,Weiqiang Qian
Ruixian Zhu
DNA methylation is a conserved epigenetic modification that plays important roles in silencing transposable elements, regulating gene expression, and maintaining genome stability. In plants, DNA methylation is de novo established by the RNA...
The multitalented TIP60 chromatin remodeling complex: wearing many hats in epigenetic regulation, cell division and diseases [0.03%]
多功能的TIP60 组蛋白乙酰化酶复合体:表观遗传调控、细胞分裂及疾病中的多面手角色
Maria Virginia Santopietro,Diego Ferreri,Yuri Prozzillo et al.
Maria Virginia Santopietro et al.
The TIP60 complex is an evolutionarily conserved, multifunctional chromatin remodeling complex involved in critical cellular processes, including DNA repair, transcription regulation, and cell cycle control. Although its molecular organizat...
Detecting Protein-DNA binding in single molecules using antibody guided methylation [0.03%]
基于抗体介导的甲基化的单分子蛋白- DNA 结合检测技术
Apoorva Thatavarty,Naor Sagy,Michael R Erdos et al.
Apoorva Thatavarty et al.
Characterization of DNA binding sites for specific proteins is of fundamental importance in molecular biology. It is commonly addressed experimentally by chromatin immunoprecipitation and sequencing (ChIP-seq) of bulk samples (103-107 cells...
Bath: a Bayesian approach to analyze epigenetic transitions reveals a dual role of H3K27me3 in chondrogenesis [0.03%]
巴斯浴:一种贝叶斯方法分析表观遗传转变揭示H3K27me3在软骨发生中的双重作用
Christoph Neu,Manuela Wuelling,Christoph Waterkamp et al.
Christoph Neu et al.
Background: Histone modifications are key epigenetic regulators of cell differentiation and have been intensively studied in many cell types and tissues. Nevertheless, we still lack a thorough understanding of how combina...
Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum [0.03%]
疟原虫调控基因座中转录增强子的功能表征
Natalia Marta Zmarlak-Feher,Kathryn S Taquet,Renée Zakhia et al.
Natalia Marta Zmarlak-Feher et al.
Background: Anopheles mosquitoes and the malaria parasites they transmit remain a significant global health problem. Most genomic and functional genomic studies of mosquitoes have focused on the protein-coding genome, and...
Floris Honig,Adele Murrell
Floris Honig
Epigenetic factors underlie cellular identity through the regulation of transcriptional networks that establish a cell's phenotype and function. Cell conversions are directed by transcription factor binding at target DNA which induce change...
Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine [0.03%]
癌症表观基因组的人工智能研究:泛癌检测及精准医疗进展综述
Karishma Sahoo,Prakash Lingasamy,Masuma Khatun et al.
Karishma Sahoo et al.
DNA methylation is a fundamental epigenetic modification that regulates gene expression and maintains genomic stability. Consequently, DNA methylation remains a key biomarker in cancer research, playing a vital role in diagnosis, prognosis,...
Carla Caniçais,Sara Vasconcelos,Fátima Santos et al.
Carla Caniçais et al.
Oocyte maturation involves both nuclear and cytoplasmic processes that are critical for the acquisition of oocyte competence. Granulosa cells, surrounding the oocyte, play a pivotal role in the maturation process, with mechanisms such as cA...
Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators [0.03%]
常见转录因子和染色质调节因子在启动子和增强子处稳定共hesin蛋白质复合物
Audra F Bryan,Megan Justice,Alexis V Stutzman et al.
Audra F Bryan et al.
Background: Cohesin is a major regulator of three-dimensional genome organization and gene expression. Cohesin associates with DNA and dynamically extrudes a DNA loop, often bringing two cis-regulatory elements physically...