Correction: From chromosomal protein disorder to chromatin phase separation [0.03%]
订正:从染色体蛋白紊乱到染色质相分离
James R Davie,Juan Ausió
James R Davie
Published Erratum
Epigenetics & chromatin. 2026 Jul 30;19(1):31. DOI:10.1186/s13072-026-00689-8 2026
EBER-associated promoter contacts mark accessible but transcriptionally constrained RNAPII promoter hubs in EBV-positive B cells [0.03%]
EBER相关的启动子接触标记了EB病毒阳性B细胞中可访问但转录上受限制的RNAPII启动子中心区
Shaik Ismail Mohammed Thangameeran,Hemalatha Mani,Chih-Wen Peng
Shaik Ismail Mohammed Thangameeran
Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) are abundant viral noncoding RNAs that associate with host chromatin, but the promoter-scale consequences of those contacts remain unclear. We re-analyzed GSE281522 in EBV-positive GM12878...
Human Alu loci gain enhancer-type epigenetic modifications in monocytes during response to bacterial LPS [0.03%]
人Alu基因座在单核细胞中响应细菌LPS时获得增强子型表观遗传修饰
Yonghao Pan,Kenji Ichiyanagi
Yonghao Pan
Background: Bacterial lipopolysaccharide (LPS) potently activates innate immunity. Transposable elements (TEs), particularly lineage-specific short interspersed elements (SINEs), have been implicated in immune regulatory ...
Bivalent chromatin states and epigenetic priming in cotton: the role of H3K4me3 and H3K27me3 in cold stress memory and resilience [0.03%]
棉花双价染色质状态和表观遗传预置:H3K4me3和H3K27me3在冷胁迫记忆和恢复力中的作用
Mayamiko Masangano,Ahmed Nasre,Ferehewoit Deressegn Lakew et al.
Mayamiko Masangano et al.
Cold stress is a significant challenge to cotton (Gossypium hirsutum L.) production during seed emergence and early seedling establishment, as cotton is native to tropical and subtropical environments. Low temperatures during these sensitiv...
CancerSubtyper: a deep learning framework for cancer subtyping through DNA methylation data [0.03%]
癌症亚型分类器:通过DNA甲基化数据进行癌症分型的深度学习框架
Joung Min Choi,Yat Fei Cheung,Liqing Zhang
Joung Min Choi
Background: Molecular subtyping is essential for precision oncology, enabling the classification of tumors into biologically and clinically relevant categories. DNA methylation has emerged as a promising biomarker for can...
The marsupial imprinted gene MLH1 has retrocopies in three marsupial families [0.03%]
有袋目动物MLH1印迹基因的假基因化及其在三个目的分布
Jenna Pride,Geoff Shaw,Marilyn B Renfree et al.
Jenna Pride et al.
Background: The mut-L homologue 1 gene (MLH1) is a DNA repair gene. Loss of biallelic expression of MLH1 in humans leads to increased predisposition to several cancer types. In the koala (Phascolarctos cinereus) and brush...
Pathway-level epigenetic modeling illuminates the methylation architecture to asthma risk across tissues [0.03%]
路径水平表观遗传学建模揭示了哮喘风险的甲基化架构跨组织分布状况
Zhongting Huang,Yuxin Liu,Fuqiang Cai et al.
Zhongting Huang et al.
Background: Asthma is a clinically heterogeneous airway disorder characterized by complex interactions between environmental exposures, immune activation, and molecular regulatory programs, whose underlying mechanisms are...
Role of LDHA in senescent fibroblast exosomes promoting ferroptosis via histone lactylation-mediated ACSL4 regulation in skin photoaging [0.03%]
组蛋白乳酸化介导的乙酰辅酶A合成酶长链脂肪酸转移酶4调节在皮肤光老化中衰老成纤维细胞外泌体通过LDHA促进铁死亡的作用
Tingting Yan,Lixia Huang,Jingjing Tao et al.
Tingting Yan et al.
Objective: This study aimed to elucidate the mechanism of Lactate Dehydrogenase A (LDHA) in senescent fibroblast-derived exosomes during skin photoaging, focusing on the molecular pathway by which it regulates Acyl-CoA Sy...
Epigenetic and chromatin remodeling mechanisms across cardiomyopathies: a comprehensive review [0.03%]
心肌病的表观遗传和染色质重塑机制:全面综述
Prabin Upadhyaya
Prabin Upadhyaya
Cardiomyopathies constitute a heterogeneous group of myocardial disorders representing leading causes of heart failure and cardiovascular mortality worldwide. While genetic mutations have been extensively characterized across different card...
H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects [0.03%]
急性髓系白血病细胞中H1.3去耗竭导致组蛋白变体H1.2重新分布、染色质重塑及细胞周期缺陷
Clara Tellez-Quijorna,Lia NGuyen,Núria Serna-Pujol et al.
Clara Tellez-Quijorna et al.
Linker histone H1 variants play critical, yet distinct, roles in chromatin organization and gene regulation. However, their specificity in cancer cells is not well understood. Our previous studies have shown that acute myeloid leukemia (AML...