Correction [0.03%]
改正
Published Erratum
Future medicinal chemistry. 2026 Mar 4:1. DOI:10.1080/17568919.2026.2641873 2026
The future of hyperuricemia management: integrating recombinant uricase and mRNA therapeutics [0.03%]
高尿酸血症管理的未来：重组尿酸酶和mRNA疗法的整合
Pooja A Chawla
Pooja A Chawla
Structural insights of mycobacterial ATP synthase and recent updates on molecular recognition of Mtb ATP synthase inhibitors: a review [0.03%]
结核分枝杆菌ATP合成酶结构研究及Mtb ATP合成酶抑制剂分子识别机制研究进展综述
Ekta Patel,Bhumika Patel
Ekta Patel
In mycobacteria, the F1Fo-ATP synthase enzyme comprises five polypeptide chains (Chain α, β, γ, ε, δ) and three subunits (Subunit a, b, and c), respectively. ATP is fundamental for the survival and growth of mycobacterial strains. In t...
Medicinal chemistry approaches for dual inhibition of amyloid-β and tau aggregation in Alzheimer's disease [0.03%]
阿尔茨海默病中抑制淀粉样蛋白和tau蛋白凝聚的医药化学方法研究
Jatin Jangra,Isha Mahindru,Aman Kumar et al.
Jatin Jangra et al.
Proteinopathies play a complex interplay in the pathogenesis of multifactorial neurological disorders. In Alzheimer's disease (AD), the extracellular deposition of amyloid-β (Aβ) plaques and intracellular accumulation of hyperphosphorylat...
Novel isocoumarin-pyrazole hybrids: synthesis, characterization, and investigation of their carbonic anhydrase inhibitory activities [0.03%]
新型异香豆素-吡唑杂化物的合成、表征及抗碳酸酐酶活性研究
Mehmet Onyilmaz,Mustafa Degirmenci,Simone Giovannuzzi et al.
Mehmet Onyilmaz et al.
Aim: Selective inhibition of tumor-associated carbonic anhydrase (CA) isoforms IX and XII is a key challenge in anticancer drug discovery, as most inhibitors cause off-target inhibition of cytosolic enzymes. We addressed ...
Design, synthesis, and biological evaluation of cycloarylchalcone derivatives as microtubule inhibitors targeting breast cancer cells [0.03%]
设计、合成及生物活性评价环芳基查尔酮衍生物作为微管抑制剂靶向乳腺癌细胞
Azra Yasmin,Ritesh Jha,Purabi Saha et al.
Azra Yasmin et al.
Aim: The increasing burden of breast cancer and drug resistance highlights the need for new chemotherapeutic agents. This study aimed to design and evaluate novel cycloarylchalcone derivatives as potential anticancer cand...
Bioactive oxadiazolo-benzodiazepines: synthesis, α amylase inhibition, antioxidant activity, molecular docking and DFT calculation [0.03%]
生物活性噁二唑-苯并二氮杂卓的合成、α淀粉酶抑制作用、抗氧化活性以及分子对接和DFT计算
Marouane Ait Lahcen,Wissal El Karfi,Nouhaila Ait Lahcen et al.
Marouane Ait Lahcen et al.
Aim: This study aimed to design, synthesize, and biologically evaluate new oxadiazolo-benzodiazepine derivatives integrating two pharmacologically relevant scaffolds, and to investigate their antidiabetic and antioxidant ...
Spiropyrrolizine derivatives as multitarget antidiabetic agents in obese type 2 diabetes: integrated in silico, in vitro, and in vivo evaluation of DPP-4 inhibition and hepatic enzyme modulation [0.03%]
用于肥胖型2型糖尿病的多靶抗糖尿病化合物螺并吡咯啉衍生物：DPP-4抑制和肝脏酶调节的综合计算机辅助药物设计、体外及体内评价
Faiza I A Abdella,Dalal Alardan,Ismail Daoud et al.
Faiza I A Abdella et al.
Aims: Obesity-associated type 2 diabetes (OB-T2D) remains a major clinical challenge due to insulin resistance and the limited efficacy of current dipeptidyl peptidase-4 (DPP-4) inhibitors in addressing metabolic dysfunct...
DNA-and BSA-binding properties of dichloro(1-methallyl-3-arylmethyl-5,6-dimethylbenzimidazolin-2-ylidene)pyridine palladium(II) complexes [0.03%]
二氯（1-甲烯丙基-3-芳基甲基-5，6-二甲基苯并咪唑啉-2-亚基）吡啶配合物的DNA和BSA结合性质研究
Elvan Üstün,Neslihan Şahin,David Sémeril
Elvan Üstün
Aims: A synthesis of five palladium(II) complexes was conducted, and their binding affinities against deoxyribonucleic acid (DNA) and Bovine Serum Albumin (BSA) were evaluated. ...
Synthetic strategies and anticancer applications of benzimidazole derivatives: a review [0.03%]
苯并咪唑衍生物的合成策略及抗肿瘤应用：综述
Durga Prasad Panda,Chetna Pal,Nanaji Yerramsetti et al.
Durga Prasad Panda et al.
Benzimidazole derivatives have attracted considerable attention in anticancer drug development owing to their structural mimicry of nucleosides, which enables disruption of key biological pathways involved in tumor growth and progression. T...