James M Connorton,Janneke Balk,Jorge Rodríguez-Celma
James M Connorton
Iron plays a crucial role in biochemistry and is an essential micronutrient for plants and humans alike. Although plentiful in the Earth's crust it is not usually found in a form readily accessible for plants to use. They must therefore sen...
Morgan M Fetherolf,Stefanie D Boyd,Duane D Winkler et al.
Morgan M Fetherolf et al.
Copper zinc superoxide dismutase (Sod1) is a critical enzyme in limiting reactive oxygen species in both the cytosol and the mitochondrial intermembrane space. Sod1 dismutes superoxide anions to hydrogen peroxide and oxygen. The catalytic r...
Helena Öhrvik,Jan Aaseth,Nina Horn
Helena Öhrvik
A general principle in all cells in the body is that an essential metal - here copper - is taken up at the plasma membrane, directed through cellular compartments for use in specific enzymes and pathways, stored in specific scavenging molec...
Javier Jiménez-Lamana,Joanna Szpunar
Javier Jiménez-Lamana
The use of nickel in modern industry and in consumer products implies some health problems for the human being. Nickel allergy and nickel carcinogenicity are well-known health effects related to human exposure to nickel, either during produ...
Cellular copper homeostasis: current concepts on its interplay with glutathione homeostasis and its implication in physiology and human diseases [0.03%]
细胞铜稳态：其与谷胱甘肽稳态的相互作用及其在生理和人类疾病中的意义的概念研究
Ashima Bhattacharjee,Kaustav Chakraborty,Aditya Shukla
Ashima Bhattacharjee
Copper is a trace element essential for almost all living organisms. But the level of intracellular copper needs to be tightly regulated. Dysregulation of cellular copper homeostasis leading to various diseases demonstrates the importance o...
Elena Gammella,Paolo Buratti,Gaetano Cairo et al.
Elena Gammella et al.
The transferrin receptor (TfR1), which mediates cellular iron uptake through clathrin-dependent endocytosis of iron-loaded transferrin, plays a key role in iron homeostasis. Since the number of TfR1 molecules at the cell surface is the rate...
The role of the zinc transporter SLC30A2/ZnT2 in transient neonatal zinc deficiency [0.03%]
瞬时新生儿锌缺乏状态下锌转运体SLC30A2/ZnT2的作用机制研究
Yarden Golan,Taiho Kambe,Yehuda G Assaraf
Yarden Golan
Breast milk is the optimal nutrient mix for infants until the age of 6 months. However, in some cases, due to genetic alterations as well as nutrient deficiencies in nursing mothers, infants may suffer from inadequate levels of micronutrien...
FOXO3 promoted mitophagy via nuclear retention induced by manganese chloride in SH-SY5Y cells [0.03%]
MnCl₂诱导的 FOXO3通过促进自噬核滞留促进线粒体自噬作用
Dongmei Song,Junxiang Ma,Li Chen et al.
Dongmei Song et al.
Objectives: To evaluate the role of FOXO3 during the process of mitophagy induced by manganese chloride (MnCl2), mitochondrial dysfunction and mitophagy were detected before and after FOXO3 was knocked down in SH-SY5Y cel...
Selenoproteins are involved in antioxidant defense systems in thalassemia [0.03%]
硒蛋白参与了地中海贫血的抗氧化防御系统中
G E Genc,Z Ozturk,S Gumuslu
G E Genc
Thalassemia major (TM) is a hereditary blood disease that affects the production of hemoglobin, resulting in severe anemia. Iron overload because of repeated blood transfusion and increased intestinal iron absorption and hemolysis are the m...
Correction: Arbuscular mycorrhizal fungi enhance the copper tolerance of Tagetes patula through the sorption and barrier mechanisms of intraradical hyphae [0.03%]
订正：丛枝菌根真菌通过内生菌丝的吸附和屏障机制增强Tagetes patulus对铜的耐性
Xishi Zhou,Lei Fu,Yan Xia et al.
Xishi Zhou et al.
Correction for 'Arbuscular mycorrhizal fungi enhance the copper tolerance of Tagetes patula through the sorption and barrier mechanisms of intraradical hyphae' by Xishi Zhou et al., Metallomics, 2017, DOI: .
Published Erratum
Metallomics : integrated biometal science. 2017 Jul 19;9(7):989. DOI:10.1039/c7mt90028g 2017