Nanoscale elemental and morphological imaging of nitrogen-fixing cyanobacteria [0.03%]
固氮蓝藻的纳米级元素和形貌成像研究
Bobby G Duersch,Steven A Soini,Yanqi Luo et al.
Bobby G Duersch et al.
Nitrogen-fixing cyanobacteria bind atmospheric nitrogen and carbon dioxide using sunlight. This experimental study focused on a laboratory-based model system, Anabaena sp., in nitrogen-depleted culture. When combined nitrogen is scarce, the...
Decreased spinal cord motor neuron numbers in mice depleted of central nervous system copper [0.03%]
中枢神经系统铜缺乏小鼠的脊髓运动神经元数量减少
J R Liddell,J B W Hilton,Y J Wang et al.
J R Liddell et al.
Disrupted copper availability in the central nervous system (CNS) is implicated as a significant feature of the neurodegenerative disease amyotrophic lateral sclerosis (ALS). Solute carrier family 31 member 1 (Slc31a1; Ctr1) governs copper ...
Insight into brain metallothioneins from bidirectional Zn2+ signaling in synaptic dynamics [0.03%]
双向锌信号在突触动态中的脑金属硫蛋白的作用机制初探
Atsushi Takeda,Haruna Tamano
Atsushi Takeda
The basal levels as the labile Zn2+ pools in the extracellular and intracellular compartments are in the range of ∼10 nM and ∼100 pM, respectively. The influx of extracellular Zn2+ is used for memory via cognitive activity and is regulate...
Stable potassium isotope ratios in human blood serum towards biomarker development in Alzheimer's disease [0.03%]
人体血液血清中的稳定钾同位素比值向阿尔茨海默病生物标志物发展方面的研究
Brandon Mahan,Yan Hu,Esther Lahoud et al.
Brandon Mahan et al.
The Alzheimer's disease (AD)-affected brain purges K with concurrently increasing serum K, suggesting brain-blood K transferal. Here, natural stable K isotope ratios-δ41K-of human serum samples were characterized in an AD biomarker pilot s...
NtZIP5A/B is involved in the regulation of Zn/Cu/Fe/Mn/Cd homeostasis in tobacco [0.03%]
NtZIP5A/B参与烟草Zn/Cu/Fe/Mn/Cd稳态的调节
Małgorzata Palusińska,Anna Barabasz,Danuta Maria Antosiewicz
Małgorzata Palusińska
Plants grow in soils with varying concentrations of microelements, often in the presence of toxic metals e.g. Cd. To cope, they developed molecular mechanisms to regulate metal cross-homeostasis. Understanding underlying complex relationshi...
P-based referencing for correcting tissue artifacts in laser ablation-inductively coupled plasma-mass spectrometry imaging of cancer samples [0.03%]
基于P元素的参考测量法在激光消融-电感耦合等离子体质谱成像技术中校正组织样本偏差 Artifact Correction in LA-ICPMS Cancer Imaging Based on P Reference Measurement
Katharina Kronenberg,Emily Hoffmann,Lena Hiddeßen et al.
Katharina Kronenberg et al.
A referencing strategy based on the element P is presented to compensate for cryosectioning tissue artifacts in laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) data. The study examines how the gadolinium-based contra...
Dietary iron intake has long-term effects on the fecal metabolome and microbiome [0.03%]
膳食铁摄入量对粪便代谢组和微生物组有长期影响
Anastasiia Kostenko,Simone Zuffa,Hui Zhi et al.
Anastasiia Kostenko et al.
Iron is essential for life, but its imbalances can lead to severe health implications. Iron deficiency is the most common nutrient disorder worldwide, and iron dysregulation in early life has been found to cause long-lasting behavioral, cog...
Mitochondrial-targeted cyclometalated Ir(III)-5,7-dibromo/dichloro-2-methyl-8-hydroxyquinoline complexes and their anticancer efficacy evaluation in Hep-G2 cells [0.03%]
线粒体靶向型cyclometalated Ir(III)-5,7-二溴/二氯-2-甲基-8-羟基喹啉配合物及其在Hep-G2细胞中的抗癌功效评估
Ting Meng,Xiongzhi Shi,Hongfen Chen et al.
Ting Meng et al.
Both 8-hydroxyquinoline compounds and iridium (Ir) complexes have emerged as potential novel agents for tumor therapy. In this study, we synthesized and characterized two new Ir(III) complexes, [Ir(L1)(bppy)2] (Br-Ir) and [Ir(L2)(bppy)2] (C...
Enhanced axon guidance and synaptic markers in rat brains using ferric-tannic nanoparticles [0.03%]
利用三价铁鞣酸纳米颗粒增强大鼠脑内轴突导向和突触标志物表达
Jantira Sanit,Jannarong Intakhad,Aiyarin Kittilukkana et al.
Jantira Sanit et al.
Ferric-tannic nanoparticles (FTs) are now considered to be new pharmaceuticals appropriate for the prevention of brain aging and related diseases. We have previously shown that FTs could activate axon guidance pathways and cellular clearanc...