Metal maps of sclerotic hippocampi of patients with mesial temporal lobe epilepsy [0.03%]
内侧颞叶癫痫患者硬化海马的金属组分图谱
Miloš Opačić,Aleksandar J Ristić,Danijela Savić et al.
Miloš Opačić et al.
The loss of metal homeostasis has been implicated in the pathophysiology of mesial temporal lobe epilepsy associated with hippocampal sclerosis (mTLE-HS). Here we applied laser ablation inductively coupled plasma mass spectrometry imaging t...
Trace element-protein interactions in endolymph from the inner ear of fish: implications for environmental reconstructions using fish otolith chemistry [0.03%]
鱼类内耳终淋巴中微量元素与蛋白质的相互作用及其对鱼类耳石化学环境重建的意义
Oliver R B Thomas,Katherine Ganio,Blaine R Roberts et al.
Oliver R B Thomas et al.
Otoliths, the biomineralised hearing "ear stones" from the inner ear of fish, grow throughout the lifespan of an individual, with deposition of alternating calciferous and proteinaceous bands occurring daily. Trace element : calcium ratios ...
Biochemical characterization of the selenoproteome in Gallus gallus via bioinformatics analysis: structure-function relationships and interactions of binding molecules [0.03%]
生物信息学分析家禽硒蛋白组的生化特征：结构-功能关系及结合分子的相互作用
Shi-Yong Zhu,Xue-Nan Li,Xiao-Chen Sun et al.
Shi-Yong Zhu et al.
Knowledge about mammalian selenoproteins is increasing. However, the selenoproteome of birds remains considerably less understood, especially concerning its biochemical characterization, structure-function relationships and the interactions...
Zinc transport and the inhibition of the L-type calcium channel are two separable functions of ZnT-1 [0.03%]
锌转运和抑制L型钙通道是ZnT-1的两种可分离的功能
Eden Shusterman,Ofer Beharier,Shiri Levy et al.
Eden Shusterman et al.
Traditionally, proteins are considered to perform a single role, be it as an enzyme, a channel, a transporter or as a structural scaffold. However, recent studies have described moonlighting proteins that perform distinct and independent fu...
Longitudinal assessment of metal concentrations and copper isotope ratios in the G93A SOD1 mouse model of amyotrophic lateral sclerosis [0.03%]
铜浓度和铜同位素比率的纵向评估：G93A SOD1渐冻症小鼠模型中的测定
T Gabriel Enge,Heath Ecroyd,Dianne F Jolley et al.
T Gabriel Enge et al.
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease, which involves progressive motor neuron degeneration in the central nervous system (CNS). The G93A SOD1 mouse model simulates one of the most common causes of familial ALS throu...
Smriti Verma,Bobby J Cherayil
Smriti Verma
Anemia is a frequent complication of many inflammatory disorders, including inflammatory bowel disease. Although the pathogenesis of this problem is multifactorial, a key component is the abnormal elevation of the hormone hepcidin, the cent...
M Aschner,C Palinski,M Sperling et al.
M Aschner et al.
Systemic trafficking and storage of essential metal ions play fundamental roles in living organisms by serving as essential cofactors in various cellular processes. Thereby metal quantification and localization are critical steps in underst...
Selenium in the prevention of atherosclerosis and its underlying mechanisms [0.03%]
硒在动脉粥样硬化防治中的作用及机制研究
Hongmei Liu,Huibi Xu,Kaixun Huang
Hongmei Liu
Atherosclerosis and related cardiovascular diseases (CVDs) represent the greatest threats to human health worldwide. Selenium, an essential trace element, is incorporated into selenoproteins that play a crucial role in human health and dise...
Effect of Cu(ii) on in vitro glycation of human serum albumin by methylglyoxal: a LC-MS-based proteomic approach [0.03%]
铜离子对甲基糖基化人血清白蛋白的体外作用：基于LC-MS的蛋白质组学方法研究
Alejandra Sarahi Ramirez Segovia,Kazimierz Wrobel,Francisco Javier Acevedo Aguilar et al.
Alejandra Sarahi Ramirez Segovia et al.
It has been reported that glycation of human serum albumin (HSA) changes its capability for copper binding whereas the increase of free copper might have an impact on protein glycation - a key process in diabetes progression. In this work, ...
Defining the human copper proteome and analysis of its expression variation in cancers [0.03%]
人类铜蛋白组的定义及其在癌症中表达变异的分析
S Blockhuys,E Celauro,C Hildesjö et al.
S Blockhuys et al.
Copper (Cu) is essential for living organisms, and acts as a cofactor in many metabolic enzymes. To avoid the toxicity of free Cu, organisms have specific transport systems that 'chaperone' the metal to targets. Cancer progression is associ...
Randomized Controlled Trial
Metallomics : integrated biometal science. 2017 Feb 22;9(2):112-123. DOI:10.1039/c6mt00202a 2017