A dietary isothiocyanate-enriched moringa (Moringa oleifera) seed extract improves glucose tolerance in a high-fat-diet mouse model and modulates the gut microbiome [0.03%]
异硫氰酸盐补充辣木籽提取物改善高脂饮食小鼠的糖耐量并调节肠道微生物群
Asha Jaja-Chimedza,Li Zhang,Khea Wolff et al.
Asha Jaja-Chimedza et al.
Moringa oleifera (moringa) has been traditionally used for the treatment of diabetes and in water purification. We previously showed that moringa seed extract (MSE), standardized to its primary bioactive isothiocyanate (MIC-1), modulated in...
Mucoadhesive role of tamarind xyloglucan on inflammation attenuates ulcerative colitis [0.03%]
热带豆胶xyloglucan的粘膜粘附作用对溃疡性结肠炎的抗炎效果
Srinivasan Periasamy,Chia-Hui Lin,Balaji Nagarajan et al.
Srinivasan Periasamy et al.
Tamarind xyloglucan (TXG) is edible, bioavailable and mucoadhesive polysaccharide. The aim of this study was (i) to investigate molecular docking studies on the interaction of TXG to MUC1 and cytokine receptors and (ii) to assess the mucoad...
Antioxidant and angiotensin-I converting enzyme inhibitory activities of phenolic extracts and fractions derived from three phenolic-rich legume varieties [0.03%]
三种富含酚类的豆类品种的抗氧化和血管紧张素转化酶抑制活性
Yan Zhang,Tibor Pechan,Sam K C Chang
Yan Zhang
Lentil, black soybean and black turtle bean are commonly consumed legumes of different genera, containing high phenolic contents, which are effective antioxidants and angiotensin-I converting enzyme (ACE) inhibitors. However, these legumes'...
Physicochemical differences between malanga (Xanthosoma sagittifolium) and potato (Solanum tuberosum) tubers are associated with differential effects on the gut microbiome [0.03%]
番荔枝块茎和土豆块茎的理化差异与对肠道微生物组的影响不同有关
Brittany L Graf,Li Zhang,Maria G Corradini et al.
Brittany L Graf et al.
Malanga (Xanthosoma sagittifolium) is used as a medicinal food for infant development and gastritis. We compared the physicochemical properties and gut microbial effects of malanga versus potato (Solanum tuberosum) using nutritional analysi...
Strategies to promote abundance of Akkermansia muciniphila, an emerging probiotics in the gut, evidence from dietary intervention studies [0.03%]
促进肠道益生菌阿克曼氏菌丰度的策略：饮食干预研究证据
Kequan Zhou
Kequan Zhou
Akkermansia muciniphila is a mucin-degrading bacterium commonly found in human gut. A. muciniphila has been inversely associated with obesity, diabetes, inflammation, and metabolic disorders. Due to its highly promising probiotic activities...
α-Glucosidase inhibiting activity and bioactive compounds of six red wine grape pomace extracts [0.03%]
六种红葡萄酒酒渣提取物的葡萄糖苷酶抑制活性及其生物活性成分研究
Hoda C Kadouh,Shi Sun,Wenjun Zhu et al.
Hoda C Kadouh et al.
Grape pomace contains considerable amounts of polyphenols and it has been reported to exhibit specific inhibitory activity against mammalian intestinal α-glucosidases. This study aims to investigate the anti-diabetes potential of Chambourc...
Bioactivity-guided isolation and purification of α-glucosidase inhibitor, 6- O- D-glycosides, from Tinta Cão grape pomace [0.03%]
以葡萄皮渣中α-糖苷酶抑制剂6- O- D-糖基化物为目标的活性追踪分离及纯化
Shi Sun,Hoda Chaouki Kadouh,Wenjun Zhu et al.
Shi Sun et al.
Bioactivity-guided fractionation methods were used to identify and purify active components in Tinta Cão grape pomace extract (GPE) that inhibit intestinal α-glucosidases. One active α-glucosidase inhibitor and one new natural product de...
Synergistic effect of black tea polyphenol, theaflavin-3,3'-digallate with cisplatin against cisplatin resistant human ovarian cancer cells [0.03%]
茶黄素-3，3'- digallate与顺铂对顺铂耐药人卵巢癌细胞的协同作用研究
Haibo Pan,Jin Li,Gary O Rankin et al.
Haibo Pan et al.
Theaflavin-3, 3'-digallate (TF3) is a phenolic compound extracted from black tea. We previously demonstrated that TF3 selectively inhibited ovarian cancer cells. Ovarian cancer has high death rate because of acquired cisplatin resistance. W...
Comparative bio-accessibility, bioavailability and bioequivalence of quercetin, apigenin, glucoraphanin and carotenoids from freeze-dried vegetables incorporated into a baked snack versus minimally processed vegetables: Evidence from in vitro models and a human bioavailability study [0.03%]
与最低限度加工蔬菜相比，冻干蔬菜掺入烘烤零食中对芦丁、芹菜素、球兰苷和类胡萝卜素的体外生物可及性、生物利用度和生物等效性的比较：来自人体生物利用度研究的证据
Natalia Perez-Moral,Shikha Saha,Mark Philo et al.
Natalia Perez-Moral et al.
The aim was to incorporate vegetables containing the phytochemicals quercetin, apigenin, glucoraphanin and carotenoids into a processed potato-based snack and assess their bioaccessibility and bioavailability. Three different processing rou...
Dried Plum Polyphenolic Extract Combined with Vitamin K and Potassium Restores Trabecular and Cortical Bone in Osteopenic Model of Postmenopausal Bone Loss [0.03%]
干制李子多酚提取物联合维生素K和钾恢复围绝经期骨丢失骨小梁和皮质骨的量效关系研究
Jennifer L Graef,Ping Ouyang,Yan Wang et al.
Jennifer L Graef et al.
Dried plum has unique anabolic effects on bone, but the responsible bioactive components have remained unclear. This study investigated components of dried plum with potential osteoprotective activity utilizing aged, osteopenic Sprague Dawl...