Beate Winner,Daniela M Vogt-Weisenhorn,Chichung D Lie et al.
Beate Winner et al.
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting 0.7% of the elderly population (defined as over 65 years of age). PD is clinically characterized by resting tremor, muscular ...
Psychopathology in multiple sclerosis: diagnosis, prevalence and treatment [0.03%]
多发性硬化症的精神病理学：诊断、流行率和治疗
Ida S Haussleiter,Martin Brüne,Georg Juckel
Ida S Haussleiter
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system. Demyelinization of nerve fibres not only affects the motor and sensory systems functionally, but may also cause psychopathological signs and symptoms....
Immunomodulation and postpartum relapses in patients with multiple sclerosis [0.03%]
免疫调节与多发性硬化病患者的产后复发关系研究
Kerstin Hellwig,Christian Beste,Sebastian Schimrigk et al.
Kerstin Hellwig et al.
Multiple sclerosis (MS) mainly affects young women during a life period with desire for children. Relapse rate decreases during pregnancy and rises after delivery. Therefore, studies on satisfactory postpartum relapse prevention and its eff...
Rob J van Marum
Rob J van Marum
Discordant findings in color-coded duplex-sonography and magnetic resonance angiography in symptomatic internal carotid artery stenosis: implications for diagnostic work-up and early intervention [0.03%]
彩色编码双通道声纳检查和磁共振血管造影对颈内动脉狭窄诊断不一致的病因及早期治疗意义：一项针对有症状患者的病例研究
Jens Eyding,Christos Krogias,Marcus Seemann et al.
Jens Eyding et al.
Background: Magnetic resonance angiography (MRA) is supposed to be the new 'gold standard' in the diagnosis of atherosclerotic disease of the extracranial arteries. ...
Tjalf Ziemssen,Heinz Reichmann
Tjalf Ziemssen
Although extrapyramidal diseases are commonly thought to solely affect the extrapyramidal motor system, nonmotor symptoms such as behavioural abnormalities, dysautonomia, sleep disturbances and sensory dysfunctions are also frequently obser...
Hamid Sadeghian,Steven Vernino
Hamid Sadeghian
Paraneoplastic neurological disorders (PNDs) are a rare and diverse group of neurological conditions that can involve any part of the nervous system. Diagnosis is facilitated by finding well-recognized autoantibodies directed against neural...
Peter Berlit
Peter Berlit
Vasculitides are characterized by inflammation and necrosis of the blood vessel wall. Large vessels including the aorta are affected in giant-cell arteritis, medium-size arteries in classic polyarteritis nodosa. The small-vessel vasculitide...
A randomized, blinded, parallel-group, pilot trial of mycophenolate mofetil (CellCept) compared with interferon beta-1a (Avonex) in patients with relapsing-remitting multiple sclerosis [0.03%]
甲基强的松龙与干扰素治疗复发缓解型多发性硬化症患者的随机盲法平行分组试点研究
Elliot M Frohman,Gary Cutter,Gina Remington et al.
Elliot M Frohman et al.
Background: Mycophenolate mofetil (MMF, CellCept®) has been utilized as an antirejection agent in transplant recipients and in patients with myriad autoimmune disorders including multiple sclerosis (MS). ...
A one-year prospective, randomized, placebo-controlled, quadruple-blinded, phase II safety pilot trial of combination therapy with interferon beta-1a and mycophenolate mofetil in early relapsing-remitting multiple sclerosis (TIME MS) [0.03%]
关于干扰素β-1a与霉酚酸酯联合治疗早期复发缓解型多发性硬化的安全性的前瞻性随机双盲安慰剂对照II期试点研究(TIME MS研究)
Gina M Remington,Katherine Treadaway,Teresa Frohman et al.
Gina M Remington et al.
Background: Mycophenolate mofetil (MMF) is an oral DNA base synthesis inhibitor with immunomodulatory effects on B cells, T cells, and macrophages. Object...