An update on the management of chronic inflammatory demyelinating polyneuropathy [0.03%]
慢性炎症性脱髓鞘多发性神经病的治疗进展
Kenneth C Gorson
Kenneth C Gorson
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated disorder of the peripheral nervous system with clinical features that include weakness, sensory loss, imbalance, pain and impaired ambulation which may lead to s...
Assessment scales in dementia [0.03%]
痴呆症评估量表
Bart Sheehan
Bart Sheehan
Dementia involves progressive and often remorseless decline in cognition, function, behaviour and care needs. Assessment in dementia relies on collateral as well as patient-derived information. Many assessment scales have been developed ove...
Mirko Bibl,Hermann Esselmann,Jens Wiltfang
Mirko Bibl
Neurochemical biomarkers for diagnosing dementias are currently under intensive investigation and the field is rapidly expanding. The main protagonists and the best defined among them are cerebrospinal fluid levels of Aβ42, tau and its pho...
Kousuke Kanemoto,Yukari Tadokoro,Tomohiro Oshima
Kousuke Kanemoto
Apart from the rather rare ictal psychotic events, such as non-convulsive status epilepticus, modern epileptic psychoses have been categorized into three main types; chronic and acute interictal psychoses (IIPs) and postictal psychosis (PIP...
Anne H Cross,Robyn S Klein,Laura Piccio
Anne H Cross
In multiple sclerosis (MS), the presence of B cells, plasma cells and excess immunoglobulins in central nervous system lesions and in the cerebrospinal fluid implicate the humoral immune system in disease pathogenesis. However, until the ad...
Karel Sonka,Marek Susta
Karel Sonka
Central hypersomnias are diseases manifested in excessive daytime sleepiness (EDS) not caused by disturbed nocturnal sleep or misaligned circadian rhythms. Central hypersomnias includes narcolepsy with and without cataplexy, recurrent hyper...
Herpesvirus infections of the central nervous system in immunocompromised patients [0.03%]
免疫功能不全患者的中枢神经系统疱疹病毒感染
Uta Meyding-Lamadé,Cornelia Strank
Uta Meyding-Lamadé
Human herpesviruses may cause infections of the central nervous system during primary infection or following reactivation from a latent state. Especially in immunosuppressed patients the infection can take a life-threatening course, and the...
White matter dementia [0.03%]
白质性痴呆症
Christopher M Filley
Christopher M Filley
White matter dementia (WMD) is a syndrome introduced in 1988 to highlight the potential of cerebral white matter disorders to produce cognitive loss of sufficient severity to qualify as dementia. Neurologists have long understood that such ...
Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity [0.03%]
多发性硬化对症治疗：大麻素在治疗肌痉挛中的作用
Verena Isabell Leussink,Leila Husseini,Clemens Warnke et al.
Verena Isabell Leussink et al.
A large proportion of patients with multiple sclerosis (MS) have spasticity, which has a marked impact on their quality of life. Anecdotal evidence suggests a beneficial effect of cannabis on spasticity as well as pain. Recently, randomized...
Multiple sclerosis and pregnancy: experience from a nationwide database in Germany [0.03%]
德国全国数据库的多发性硬化症与妊娠经验
Kerstin Hellwig,Aiden Haghikia,Milena Rockhoff et al.
Kerstin Hellwig et al.
Objective: The objective of this study was to evaluate exposure to disease-modifying therapies (DMTs) during pregnancy in 335 pregnancies of multiple sclerosis (MS) patients and to further determine whether exclusive brea...