Phylogenomic analysis of polyketide synthase genes in actinomycetes: structural analysis of KS domains and modules of polyketide synthases [0.03%]
放线菌聚酮合酶基因的系统发生及结构分析：PKS-KS结构域和模块的结构分析
Samreen Sarwar,Mehboob Ahmed,Shahida Hasnain
Samreen Sarwar
Polyketides are complex and diverse secondary metabolites, synthesised by large multifunctional enzymes, Polyketide Synthases (PKS). The phylogenomic analysis of β-ketosynthase (KS) domains and PKSs within actinomycetes suggests the contri...
Bio-image informatics [0.03%]
生物影像信息学
Tianming Liu,Fuhui Long
Tianming Liu
Jianfeng Lu,Tao Wu,Lei Cheng et al.
Jianfeng Lu et al.
Quantitative analysis of image-based phenotype is of significant importance in zebrafish image analysis and high-content screening. In this paper, an automatic analysis pipeline is proposed for quantification of the curvedness of zebrafish ...
Improving segmentation of 3D touching cell nuclei using flow tracking on surface meshes [0.03%]
基于表面网格的流跟踪在三维细胞核分割中的应用
Gang Li,Lei Guo
Gang Li
Automatic segmentation of touching cell nuclei in 3D microscopy images is of great importance in bioimage informatics and computational biology. This paper presents a novel method for improving 3D touching cell nuclei segmentation. Given bi...
Subrajeet Mohapatra,Dipti Patra,Kundan Kumar
Subrajeet Mohapatra
Leukocyte image segmentation acts as the foundation for all automated image based hematological disease recognition systems. Perfection in image segmentation is a necessary condition for improving the diagnostic accuracy in automated cytolo...
Mark R Winter,Cheng Fang,Gary Banker et al.
Mark R Winter et al.
Multitemporal Association Tracking (MAT) is a new graph-based method for multitarget tracking in biological applications that reduces the error rate and implementation complexity compared to approaches based on bipartite matching. The data ...
Entropy based unsupervised Feature Selection in digital mammogram image using rough set theory [0.03%]
基于粗糙集理论的熵特征选择算法在数字乳腺图像中的应用研究
C Velayutham,K Thangavel
C Velayutham
Feature Selection (FS) is a process, which attempts to select features, which are more informative. In the supervised FS methods various feature subsets are evaluated using an evaluation function or metric to select only those features, whi...
Research on segmentation of dorsal diencephalon and ventral midbrain of zebrafish embryo based on active contour model [0.03%]
基于主动轮廓模型的斑马鱼胚胎背脑中脑边界分割研究
Tao Wu,Jianfeng Lu,Yanting Lu et al.
Tao Wu et al.
Zebrafish is a valuable vertebrate model in life science research. In the zebrafish research, segmentation of zebrafish embryo images is a prerequisite for subsequent processing and analysis. Specifically, shape analysis of zebrafish's two ...
Using protein abundance to indicate underlying mRNA expression levels in E.coli: an SEM modelling approach [0.03%]
基于SEM模型利用蛋白丰度判断E.coli中相应的信使RNA表达水平
Jacqueline J Harris,Christine W Duarte,Michael C Mossing
Jacqueline J Harris
Do steady-state protein levels accurately predict mRNA levels? Based on the central dogma (DNA RNA protein) current protein levels are representative of mRNA present at an earlier time. However, most cellular mRNA protein comparative studie...
Discovering a potent small molecule inhibitor for gankyrin using de novo drug design approach [0.03%]
利用从头药物设计方法发现针对Gankyrin的高效小分子抑制剂
Prasoon Kumar Thakur,Imtaiyaz Hassan
Prasoon Kumar Thakur
Gankyrin is an oncoprotein composed of six ankyrin repeats, over-expressed in the Hepatocellular Carcinoma (HCC), and directly involved in the cell cycle regulation. Therefore, it is a potential drug target to restrict the growth of cancer ...