Propofol-Facilitated Recovery Sleep Modulates Cognitive Function via Slow Oscillation-Spindle Coupling After Acute Sleep Deprivation in Rats [0.03%]
异丙酚促进恢复性睡眠通过慢振荡-纺锤波偶联改善急性睡眠剥夺大鼠的认知功能
Chenyi Yang,Huan Liu,Xinyi Wang et al.
Chenyi Yang et al.
Background: Sleep deprivation (SD) is common but underrecognized in intensive care unit (ICU) patients and contributes to delirium and long-term neurocognitive deficits. Propofol is widely used for titratable ICU sedation...
Dynamic Hemispheric Lateralization of Naturalistic Emotional Processing After Unilateral Stroke: An EEG Study [0.03%]
卒中后自然情绪处理的半球侧化的动态变化：一项EEG研究
Menglin Han,Yuting Tang,Yunyi Lv et al.
Menglin Han et al.
Aim: Emotional impairment is common after stroke, but the neural electrophysiological mechanisms by which left- and right-hemisphere lesions differentially alter emotional processing remain unclear. Conventional time-aver...
CD147-Conjugated Minocycline Nanomicelles Alleviate Neuroinflammation and Improve Neurological Function Following Intracerebral Hemorrhage [0.03%]
脑出血后微囊化美罗培南纳米胶束通过共轭CD147减轻神经炎症并改善神经功能损伤
Yang Liu,Yun Chen,Yuanyuan Liu et al.
Yang Liu et al.
Background: Intracerebral hemorrhage (ICH) remains one of the most devastating subtypes of stroke, characterized by high mortality and limited therapeutic options. Neuroinflammation is recognized as a critical determinant...
Scutellarin Alleviates Neuronal Apoptosis After Ischemia and Hypoxia via the HIF-1α-CX3CR1 Axis [0.03%]
鼠李茋通过HIF-1α-CX3CR1轴抑制缺血缺氧诱导的神经元凋亡
Jingchun Pei,Bin Hu,Zhonghui Wen et al.
Jingchun Pei et al.
Background: Stroke is a significant health threat characterized by high incidence, mortality, disability, recurrence, and complications. Over 70% of strokes are ischemic in nature. Reducing neuronal apoptosis following is...
VMAT-DAT-Dopamine Regulatory System Involved in the Protective Effect of 3-n-Butylphthalide Against Ischemic Stroke [0.03%]
3-正丁基苯酞通过保护缺血性卒中后大鼠纹状体多巴胺能神经元减少抑郁样行为的机制研究
Xiao-Ting Zhou,Qin Liu,Ming Chen et al.
Xiao-Ting Zhou et al.
Aims: A stable uptake-release cycle system of dopamine is dependent upon two transporters, dopamine transporter (DAT) and vesicular monoamine transporter (VMAT). Whether the regulation system of dopamine is involved in th...
The Role of γδ T Cells in Ischemic Stroke: Insights From the Perspective of the Brain-Gut Axis [0.03%]
脑-肠轴视角下缺血性卒中γδT细胞的作用机制探讨研究进展
Yilin Li,Yina Li,Yang Shen et al.
Yilin Li et al.
Background: Stroke is a leading cause of disability and mortality worldwide, with ischemic stroke accounting for approximately 87% of all cases. Despite advances in reperfusion therapy, effective treatments targeting seco...
Meng Xu,Xuan Guo,Zhi-Kui Wang et al.
Meng Xu et al.
Introduction: Pathogenic variants in STXBP1 are a well-established cause of developmental and epileptic encephalopathy (DEE), whereas their contribution to milder epilepsy phenotypes remains under-characterized. We sought...
Neuromodulation Techniques in Chronic Cerebral Hypoperfusion: Mechanisms and Therapeutic Advances [0.03%]
慢性脑低灌注的神经调控技术：机制与治疗进展
Chenye Qiao,Ning Li,Congxiao Wang et al.
Chenye Qiao et al.
Background: Chronic cerebral hypoperfusion (CCH) is a major hemodynamic substrate of vascular cognitive impairment and vascular dementia, yet effective therapies with multi-target neuroprotective potential remain limited....