Modular alkyl growth in amines via the selective insertion of alkynes into C-C bonds [0.03%]
通过炔烃选择性插入C-C键实现胺类化合物的模块化烷基增长反应
Xin-Yue Zhou,Lu Liu,Hairong Lyu et al.
Xin-Yue Zhou et al.
The site-specific modification of amines has been a highly sought-after objective in organic synthesis. Despite the rapid advancement of carbon-hydrogen (C-H) bond functionalization methods, effective strategies for carbon-carbon (C-C) bond...
A designer minimalistic model parallels the phase-separation-mediated assembly and biophysical cues of extracellular matrix [0.03%]
一种极简设计模型平行于相分离介导的细胞外基质组装和生物物理线索
Xian Xie,Tianjie Li,Linjie Ma et al.
Xian Xie et al.
The propensity for controlled liquid-liquid phase separation and subsequent directed phase transition are crucial for the coacervation-mediated assembly of extracellular matrix (ECM). This spatiotemporally controlled ECM assembly can be use...
Shira Joudan
Shira Joudan
Linked in with lignin [0.03%]
与木质素联系在一起
Moses Dike,Shudipto Konika Dishari
Moses Dike
Information propagation through enzyme-free catalytic templating of DNA dimerization with weak product inhibition [0.03%]
无酶催化的DNA二聚化模板反应及其弱产物抑制下的信息传播研究
Javier Cabello-Garcia,Rakesh Mukherjee,Wooli Bae et al.
Javier Cabello-Garcia et al.
Information propagation by sequence-specific, template-catalysed molecular assembly is a key process facilitating life's biochemical complexity, yielding thousands of sequence-defined proteins from only 20 distinct building blocks. However,...
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach [0.03%]
通过网状方法利用高配位密度配体构建超微孔锆金属有机框架
Liang Yu,Shenfang Li,Xin Zhou et al.
Liang Yu et al.
The rational design and synthesis of ultramicroporous solids featuring uniform pore dimensions remains a notable challenge, yet these materials are critical for the selective discrimination of molecules with similar physicochemical properti...
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues [0.03%]
仿生MOF基多孔界面膜的构建及复杂原细胞和组织模型的功能模拟研究
Yanglimin Ji,Yiyang Lin,Yan Qiao
Yanglimin Ji
The bottom-up construction of cell-like entities or protocells is essential for emulating cytomimetic behaviours within artificial cell consortia. Complex coacervate microdroplets are promising candidates for primordial cells; however, repl...
A selenoxide for single-atom protein modification of tyrosine residues enabled by water-resistant chalcogen and hydrogen bonding [0.03%]
一种硒氧化物单原子蛋白质修饰酪氨酸残基的方法，该方法通过抗水硫族元素和氢键实现
Songyun Lin,Marina Hirao,Philipp Hartmann et al.
Songyun Lin et al.
Post-translational modifications such as phosphorylation and acetylation are often minor structural modifications that can have profound effects on protein structure and thus broaden protein functions. Nevertheless, studying these effects d...
Sandip A Bhadange,Nitin T Patil
Sandip A Bhadange
Hongwei Shi,Matthias Rudolph,Jun Li et al.
Hongwei Shi et al.
Gold redox catalysis, which exploits the ability of strong π-acid activation in combination with redox reactions, has emerged as an attractive synthetic method with unique reactivities compared to other transition metals. However, gold red...