Connor W Patrick,Yueze Gao,Prakhar Gupta et al.
Connor W Patrick et al.
Polyynes are chains of sp1 carbon atoms with alternating single and triple bonds. As they become longer, they evolve towards carbyne, the 1D allotrope of carbon, and they become increasingly unstable. It has been anticipated that long polyy...
Remote stereocontrol with azaarenes via enzymatic hydrogen atom transfer [0.03%]
基于酶的氢原子转移远程立体选择性调控氮杂芳环化合物反应路径研究
Maolin Li,Wesley Harrison,Zhengyi Zhang et al.
Maolin Li et al.
Strategies for achieving asymmetric catalysis with azaarenes have traditionally fallen short of accomplishing remote stereocontrol, which would greatly enhance accessibility to distinct azaarenes with remote chiral centres. The primary obst...
Modular and diverse synthesis of amino acids via asymmetric decarboxylative protonation of aminomalonic acids [0.03%]
基于不对称脱羧质子化草氨臂酸的氨基酸模块多样化合成
Wei-Feng Zheng,Jingdan Chen,Xiaotian Qi et al.
Wei-Feng Zheng et al.
Stereoselective protonation is a challenge in asymmetric catalysis. The small size and high rate of transfer of protons mean that face-selective delivery to planar intermediates is hard to control, but it can unlock previously obscure asymm...
Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids [0.03%]
羧酸参与的烯烃光催化环化反应合成氟代烷基化产物
Kang-Jie Bian,Yen-Chu Lu,David Nemoto Jr et al.
Kang-Jie Bian et al.
Incorporation of fluoroalkyl motifs in pharmaceuticals can enhance the therapeutic profiles of the parent molecules. The hydrofluoroalkylation of alkenes has emerged as a promising route to diverse fluoroalkylated compounds; however, curren...
Rong Ye,Xiangcheng Sun,Xianwen Mao et al.
Rong Ye et al.
Microscopic sequences of synthetic polymers play crucial roles in the polymer properties, but are generally unknown and inaccessible to traditional measurements. Here we report real-time optical sequencing of single synthetic copolymer chai...
Frankie D White,Nikki A Thiele,Megan E Simms et al.
Frankie D White et al.
The structure and bonding of radium (Ra) is poorly understood because of challenges arising from its scarcity and radioactivity. Here we report the synthesis of a molecular Ra2+ complex using 226Ra and the organic ligand dibenzo-30-crown-10...
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides [0.03%]
轴手性酰基亚胺
Fengjin Wu,Yichi Zhang,Ruiqi Zhu et al.
Fengjin Wu et al.
Atropisomerism is a type of conformational chirality that plays a critical role in various fields of chemistry, including synthetic, medicinal and material chemistry, and its impact has been widely recognized. Although chiral atropisomerism...
Gable M Wadsworth,Walter J Zahurancik,Xiangze Zeng et al.
Gable M Wadsworth et al.
Co-phase separation of RNAs and RNA-binding proteins drives the biogenesis of ribonucleoprotein granules. RNAs can also undergo phase transitions in the absence of proteins. However, the physicochemical driving forces of protein-free, RNA-d...
Superstructural ordering in self-sorting coacervate-based protocell networks [0.03%]
基于自分类凝聚滴的原细胞网络中的超分子有序结构
Wenjing Mu,Liyan Jia,Musen Zhou et al.
Wenjing Mu et al.
Bottom-up assembly of higher-order cytomimetic systems capable of coordinated physical behaviours, collective chemical signalling and spatially integrated processing is a key challenge in the study of artificial multicellularity. Here we de...