Organocatalytic aromatization-promoted umpolung reaction of imines [0.03%]
有机催化剂促进的亚胺 oxidopyrylium 阳离子介导的偶联反应及串联脱芳构化反应
Ye-Hui Chen,Meng Duan,Si-Li Lin et al.
Ye-Hui Chen et al.
The umpolung functionalization of imines bears vast synthetic potential, but polarity inversion is less efficient compared with the carbonyl counterparts. Strong nucleophiles are often required to react with the N-electrophiles without cata...
A general copper-catalysed enantioconvergent C(sp3)-S cross-coupling via biomimetic radical homolytic substitution [0.03%]
一种仿生自由基均裂取代的铜催化动力学拆分的C(sp3)-S交叉偶联反应
Yu Tian,Xi-Tao Li,Ji-Ren Liu et al.
Yu Tian et al.
Although α-chiral C(sp3)-S bonds are of enormous importance in organic synthesis and related areas, the transition-metal-catalysed enantioselective C(sp3)-S bond construction still represents an underdeveloped domain probably due to the di...
Chun-Lin Deng,Akachukwu D Obi,Bi Youan E Tra et al.
Chun-Lin Deng et al.
Substitution of a C=C bond by an isoelectronic B-N bond is a well-established strategy to alter the electronic structure and stability of acenes. BN-substituted acenes that possess narrow energy gaps have attractive optoelectronic propertie...
María L G Sansores-Paredes,Martin Lutz,Marc-Etienne Moret
María L G Sansores-Paredes
Catalytic olefin hydrogenation is ubiquitous in organic synthesis. In most proposed homogeneous catalytic cycles, reactive M-H bonds are generated either by oxidative addition of H2 to a metal centre or by deprotonation of a non-classical m...
Yiran Li,Bin Xue,Jiahui Yang et al.
Yiran Li et al.
Azobenzene has been widely explored as a photoresponsive element in materials science. Although some studies have investigated the force-induced isomerization of azobenzene, the effect of force on the rupture of azobenzene has not been expl...
Subdomain dynamics enable chemical chain reactions in non-ribosomal peptide synthetases [0.03%]
亚结构动力学使非核糖体肽合成酶发生化学链反应
Xun Sun,Jonas Alfermann,Hao Li et al.
Xun Sun et al.
Many peptide-derived natural products are produced by non-ribosomal peptide synthetases (NRPSs) in an assembly-line fashion. Each amino acid is coupled to a designated peptidyl carrier protein (PCP) through two distinct reactions catalysed ...
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly [0.03%]
利用生物催化聚合诱导自组装进行人工细胞合成
Andrea Belluati,Sètuhn Jimaja,Robert J Chadwick et al.
Andrea Belluati et al.
Artificial cells are biomimetic microstructures that mimic functions of natural cells, can be applied as building blocks for molecular systems engineering, and host synthetic biology pathways. Here we report enzymatically synthesized polyme...
Jeremy R H Tame
Jeremy R H Tame
An acid for an acid [0.03%]
以酸治酸
Xufeng Lin,Alemayehu Gashaw Woldegiorgis
Xufeng Lin
Shira Joudan
Shira Joudan