Enantioselective sulfur(VI) fluoride exchange reaction of iminosulfur oxydifluorides [0.03%]
酰亚胺硫氧二氟化物的对映选择性硫(VI)氟交换反应
Zhiyuan Peng,Shoujun Sun,Meng-Meng Zheng et al.
Zhiyuan Peng et al.
Linkage chemistry and functional molecules derived from the stereogenic sulfur(VI) centre have important applications in organic synthesis, bioconjugation, drug discovery, agrochemicals and polymeric materials. However, existing approaches ...
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts [0.03%]
操作薄膜电化学EPR光谱追踪表面固定催化剂中的自由基中间体
Maryam Seif-Eddine,Samuel J Cobb,Yunfei Dang et al.
Maryam Seif-Eddine et al.
The development of surface-immobilized molecular redox catalysts is an emerging research field with promising applications in sustainable chemistry. In electrocatalysis, paramagnetic species are often key intermediates in the mechanistic cy...
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0) [0.03%]
磷配体镍(0)催化交叉偶联反应中的氧化加成机制研究
Christina N Pierson,John F Hartwig
Christina N Pierson
The complexes of first-row transition metals can undergo elementary reactions by multiple pathways due to their propensity to undergo both one- and two-electron redox steps. Classic and recent studies of the oxidative addition of aryl halid...
A charge-neutral organic cage selectively binds strongly hydrated sulfate anions in water [0.03%]
一个电中性的有机笼子可以在水中选择性地结合强水合的硫酸盐阴离子
Liuyang Jing,Evelyne Deplazes,Jack K Clegg et al.
Liuyang Jing et al.
In biological systems, enzymes and transport proteins can bind anions in aqueous media solely by forming hydrogen bonds with charge-neutral motifs. Reproducing this functionality in synthetic systems presents challenges and incurs high cost...
Biocatalytic strategy for the construction of sp3-rich polycyclic compounds from directed evolution and computational modelling [0.03%]
定向进化和计算机建模对富sp3杂化轨道的多环化合物构建的生物催化策略
David A Vargas,Xinkun Ren,Arkajyoti Sengupta et al.
David A Vargas et al.
Catalysis with engineered enzymes has provided more efficient routes for the production of active pharmaceutical agents. However, the potential of biocatalysis to assist in early-stage drug discovery campaigns remains largely untapped. In t...
Oxidative two-state photoreactivity of a manganese(IV) complex using near-infrared light [0.03%]
近红外光照射下一个四价锰配合物的氧化双态光反应活性研究
Nathan R East,Robert Naumann,Christoph Förster et al.
Nathan R East et al.
Highly reducing or oxidizing photocatalysts are a fundamental challenge in photochemistry. Only a few transition metal complexes with Earth-abundant metal ions have so far advanced to excited state oxidants. All these photocatalysts require...
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene [0.03%]
吲哚[1,2-a]荧蒽在π-自由基开壳层与闭壳层之间的双稳态
Shantanu Mishra,Manuel Vilas-Varela,Leonard-Alexander Lieske et al.
Shantanu Mishra et al.
Indenofluorenes are non-benzenoid conjugated hydrocarbons that have received great interest owing to their unusual electronic structure and potential applications in nonlinear optics and photovoltaics. Here we report the generation of unsub...
Chelation enables selectivity control in enantioconvergent Suzuki-Miyaura cross-couplings on acyclic allylic systems [0.03%]
螯合作用使非环烯丙基系统中的不对称汇聚Suzuki-Miyaura交叉偶联反应的选择性控制成为可能
Violeta Stojalnikova,Stephen J Webster,Ke Liu et al.
Violeta Stojalnikova et al.
Asymmetric Suzuki-Miyaura cross-couplings with aryl boronic acids and allylic electrophiles are a powerful method to convert racemic mixtures into enantioenriched products. Currently, enantioconvergent allylic arylations are limited to subs...