Stereodivergent photobiocatalytic radical cyclization through the repurposing and directed evolution of fatty acid photodecarboxylases [0.03%]
脂肪酸光脱羧酶的再利用和定向进化实现立体发散式光生物催化自由基环化反应
Shuyun Ju,Dian Li,Binh Khanh Mai et al.
Shuyun Ju et al.
Despite their intriguing photophysical and photochemical activities, naturally occurring photoenzymes have not yet been repurposed for new-to-nature activities. Here we engineered fatty acid photodecarboxylases to catalyse unnatural photore...
Simon Edelmann,Jean-Philip Lumb
Simon Edelmann
Phenols and their derivatives are ubiquitous in nature and critically important industrial chemicals. Their properties are intimately linked to the relative substitution pattern of the aromatic ring, reflecting well-known electronic effects...
Steven H Bennett,Jacob S Bestwick,Vera P Demertzidou et al.
Steven H Bennett et al.
Enantioconvergent reactions are pre-eminent in contemporary asymmetric synthesis as they convert both enantiomers of a racemic starting material into a single enantioenriched product, thus avoiding the maximum 50% yield associated with reso...
Mechanically triggered on-demand degradation of polymers synthesized by radical polymerizations [0.03%]
通过机械触发按需降解自由基聚合合成的聚合物
Peng Liu,Sètuhn Jimaja,Stefan Immel et al.
Peng Liu et al.
Polymers that degrade on demand have the potential to facilitate chemical recycling, reduce environmental pollution and are useful in implant immolation, drug delivery or as adhesives that debond on demand. However, polymers made by radical...
Bioorthogonal masked acylating agents for proximity-dependent RNA labelling [0.03%]
用于邻近依赖性RNA标记的生物正交掩蔽酰化剂
Shubhashree Pani,Tian Qiu,Kaitlin Kentala et al.
Shubhashree Pani et al.
RNA localization is highly regulated, with subcellular organization driving context-dependent cell physiology. Although proximity-based labelling technologies that use highly reactive radicals or carbenes provide a powerful method for unbia...
Upcycling of polyethylene to gasoline through a self-supplied hydrogen strategy in a layered self-pillared zeolite [0.03%]
逐层自撑分子筛中通过自给氢策略将聚乙烯升级转化为汽油
Ziyu Cen,Xue Han,Longfei Lin et al.
Ziyu Cen et al.
Conversion of plastic wastes to valuable carbon resources without using noble metal catalysts or external hydrogen remains a challenging task. Here we report a layered self-pillared zeolite that enables the conversion of polyethylene to gas...
Copper-catalysed asymmetric hydroboration of alkenes with 1,2-benzazaborines to access chiral naphthalene isosteres [0.03%]
铜催化烯烃与1,2-苯并氮杂硼啉的手性不对称水合硼化反应以接近手性萘异构体
Wanlan Su,Jide Zhu,Yu Chen et al.
Wanlan Su et al.
Bioisosteric replacement has emerged as a clear strategy for drug-structure optimization. Naphthalene is the core element of many chiral pharmaceuticals and drug candidates. However, as a promising isostere of naphthalene, the chiral versio...
Tetrameric self-assembling of water-lean solvents enables carbamate anhydride-based CO2 capture chemistry [0.03%]
四聚体自组装贫水溶剂使碳酰胺酐类二氧化碳捕捉化学品成为可能
Julien Leclaire,David J Heldebrant,Katarzyna Grubel et al.
Julien Leclaire et al.
Carbon capture, utilization and storage is a key yet cost-intensive technology for the fight against climate change. Single-component water-lean solvents have emerged as promising materials for post-combustion CO2 capture, but little is kno...
Towards zero droplet friction [0.03%]
迈向零液滴摩擦
Abhinav Naga,Doris Vollmer
Abhinav Naga