Machine learning trims the peptide drug design process to a sweet spot [0.03%]
机器学习可使肽类药物设计过程达到最优甜点区
Chloe E Markey,Daniel Reker
Chloe E Markey
Chloe D Wong,Elizabeth R Jarvo
Chloe D Wong
Dynamic-to-static switch of hydrogen bonds induces a metal-insulator transition in an organic-inorganic superlattice [0.03%]
氢键的动态到静态转换诱导有机-无机超晶格中的金属-绝缘体相变
Zhenkai Xie,Rui Luo,Tianping Ying et al.
Zhenkai Xie et al.
Hydrogen bonds profoundly influence the fundamental chemical, physical and biological properties of molecules and materials. Owing to their relatively weaker interactions compared to other chemical bonds, hydrogen bonds alone are generally ...
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution [0.03%]
来源于趋同进化的含硒抗氧化剂卵硒醇的发现
Chase M Kayrouz,Kendra A Ireland,Vanessa Y Ying et al.
Chase M Kayrouz et al.
Selenium is an essential micronutrient, but its presence in biology has been limited to protein and nucleic acid biopolymers. The recent identification of a biosynthetic pathway for selenium-containing small molecules suggests that there is...
Publisher Correction: Establishing the origin of Marcus-inverted-region behaviour in the excited-state dynamics of cobalt(III) polypyridyl complexes [0.03%]
publisher correction ：建立钴 (iii) 多吡啶复合物激发态动力学中 marcus 倒置区域行为的起源
Atanu Ghosh,Jonathan T Yarranton,James K McCusker
Atanu Ghosh
Published Erratum
Nature chemistry. 2024 Oct;16(10):1732. DOI:10.1038/s41557-024-01615-9 2024
Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation [0.03%]
作者更正：植物肽cyclase再利用以实现赖氨酸酰化定位
Fabian B H Rehm,Tristan J Tyler,Yan Zhou et al.
Fabian B H Rehm et al.
Published Erratum
Nature chemistry. 2024 Sep;16(9):1565. DOI:10.1038/s41557-024-01625-7 2024
Multi-tiered chemical proteomic maps of tryptoline acrylamide-protein interactions in cancer cells [0.03%]
癌细胞中Tryptoline Acrylamide与蛋白质互作的多级化学蛋白图谱
Evert Njomen,Rachel E Hayward,Kristen E DeMeester et al.
Evert Njomen et al.
Covalent chemistry is a versatile approach for expanding the ligandability of the human proteome. Activity-based protein profiling (ABPP) can infer the specific residues modified by electrophilic compounds through competition with broadly r...
Dynamic structural twist in metal-organic frameworks enhances solar overall water splitting [0.03%]
金属有机框架中动态结构扭曲促进整体水分解制氢
Kang Sun,Yan Huang,Fusai Sun et al.
Kang Sun et al.
Photocatalytic overall water splitting holds great promise for solar-to-hydrogen conversion. Maintaining charge separation is a major challenge but is key to unlocking this potential. Here we discovered a metal-organic framework (MOF) that ...