Ketan A Ganar,Manali Nandy,Polina Turbina et al.
Ketan A Ganar et al.
Hard ticks feed on their host for multiple days. To ensure firm attachment, they secrete a protein-rich saliva that eventually forms a solid cement cone. The underlying mechanism of this liquid-to-solid transition is currently not understoo...
Russell J Wilson,Kerstin G Blank
Russell J Wilson
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles [0.03%]
吲哚和吡咯的不对称去芳构化单原子骨架构建反应
Xiaolong Zhang,Qingmin Song,Shaopeng Liu et al.
Xiaolong Zhang et al.
Heterocycle skeletal editing has recently emerged as a powerful tactic for achieving heterocycle-to-heterocycle transmutation without the need for multistep de novo heterocycle synthesis. However, the enantioselective skeletal editing of he...
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids [0.03%]
基于分子旋转体的遗传编码氨基酸的设计用于合成人工荧光蛋白和生物传感器
Liming Hu,Wenbing Cao,Yihaofan Jiang et al.
Liming Hu et al.
Fluorescent proteins are indispensable tools in biological and medical research. The fluorophores are typically encoded by the primary amino acid sequence, from which a fluorescent molecular rotor structure forms upon protein folding. Here,...
Mimicking fluorophores from nature to generate artificial fluorescent proteins and biosensors [0.03%]
仿生天然荧光分子生成人工荧光蛋白和生物传感器
Chia-Heng Hsiung,Xin Zhang
Chia-Heng Hsiung
Unmasking the reverse catalytic activity of 'ene'-reductases for asymmetric carbonyl desaturation [0.03%]
揭秘“ene”还原酶的反向催化活性以实现手性碳氧双键脱氢反应
Hui Wang,Bin Gao,Heli Cheng et al.
Hui Wang et al.
Carbonyl desaturation is a fundamental reaction widely practised in organic synthesis. While numerous methods have been developed to expand the scope of this important transformation, most of them necessitate multi-step protocols or suffer ...
The importance of integrating energy justice into chemistry graduate student research and the associated pathways and barriers [0.03%]
能源正义在化学研究生研究中的整合及其相关路径和障碍的重要性
Casey M Davis,Lacey S Roberts,Sasha R Neefe et al.
Casey M Davis et al.
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion [0.03%]
饱和环胺的氮杂缩酮插入扩环反应
Licheng Wu,Hanyu Xia,Jiahao Bai et al.
Licheng Wu et al.
Saturated N-heterocycles are ubiquitous structures among natural products and biologically active compounds. Therefore, the development of synthetic methods for the construction of N-heterocycles is of great importance in the synthetic comm...
Jack M Wootton,William P Unsworth
Jack M Wootton
Dongmin Wang,Wang Chen,Haonan Chen et al.
Dongmin Wang et al.
Nitrene radical compounds are short-lived intermediates in a variety of nitrogen-involved transformations. They feature either a singlet or a triplet ground state, depending on the electronic properties of the substituents. Triplet nitrenes...