Ghewa AlSabeh,Mengqiong Zhu,Jovana V Milić
Ghewa AlSabeh
Pawel L Urban
Pawel L Urban
Beyond grateful [0.03%]
倍感欣慰
Michelle Francl
Michelle Francl
De novo design of ribosomally synthesized and post-translationally modified peptides [0.03%]
从头设计核糖体合成和翻译后修饰的肽类抗生素
Emerson Glassey,Zhengan Zhang,Andrew M King et al.
Emerson Glassey et al.
In nature, peptides are enzymatically modified to constrain their structure and introduce functional moieties. De novo peptide structures could be built by combining enzymes from different pathways, but determining the rules of their use is...
Davide Spinnato,Nils Nöthling,Markus Leutzsch et al.
Davide Spinnato et al.
The chemistry of low-valent bismuth compounds has recently unlocked new concepts in catalysis and unique electronic structure fundamentals. In this work, we describe the synthesis and characterization of a highly reduced bismuth salt featur...
Zirui Lv,Runfeng Lin,Yi Yang et al.
Zirui Lv et al.
The synthesis of mesoporous metal-organic frameworks (meso-MOFs) is desirable as these materials can be used in various applications. However, owing to the imbalance in structural tension at the micro-scale (MOF crystallization) and the mes...
Synthesis of single-crystalline sp2-carbon-linked covalent organic frameworks through imine-to-olefin transformation [0.03%]
通过亚胺转化烯烃合成sp２碳连接的共价有机框架单晶
Shengxu Li,Shunqi Xu,En Lin et al.
Shengxu Li et al.
sp2-carbon-linked covalent organic frameworks (sp2c-COFs) are crystalline porous polymers with repeat organic units linked by sp2 carbons, and have attracted increasing interest due to their robust skeleton and tunable semiconducting proper...
Intellectual frameworks to understand complex biochemical systems at the origin of life [0.03%]
理解生命起源复杂生物化学系统的智力框架
Burckhard Seelig,Irene A Chen
Burckhard Seelig
Understanding the emergence of complex biochemical systems, such as protein translation, is a great challenge. Although synthetic approaches can provide insight into the potential early stages of life, they do not address the equally import...
Four-electron reduction of benzene by a samarium(II)-alkyl without the addition of external reducing agents [0.03%]
无需添加外部还原剂时偶联钐(II)烷基使苯发生四电子还原反应
Georgia M Richardson,Thayalan Rajeshkumar,Finlay M Burke et al.
Georgia M Richardson et al.
Benzene reduction by molecular complexes remains an important synthetic challenge, requiring harsh reaction conditions involving group I metals. Reductions of benzene, to date, typically result in a loss of aromaticity, although the benzene...
Cytoskeleton-functionalized synthetic cells with life-like mechanical features and regulated membrane dynamicity [0.03%]
具有类似生命的机械特性及可调控膜动态性的细胞骨架功能化仿生人工细胞
Sebastian Novosedlik,Felix Reichel,Thijs van Veldhuisen et al.
Sebastian Novosedlik et al.
The cytoskeleton is a crucial determinant of mammalian cell structure and function, providing mechanical resilience, supporting the cell membrane and orchestrating essential processes such as cell division and motility. Because of its funda...