Cellular mechanisms of oligoclonal vascular smooth muscle cell expansion in cardiovascular disease [0.03%]
心血管疾病中血管平滑肌细胞异倍体形成的细胞机制研究进展
Matt D Worssam,Jordi Lambert,Sebnem Oc et al.
Matt D Worssam et al.
Aims: Quiescent, differentiated adult vascular smooth muscle cells (VSMCs) can be induced to proliferate and switch phenotype. Such plasticity underlies blood vessel homeostasis and contributes to vascular disease develop...
Jan Dudek,Edoardo Bertero,Christoph Maack
Jan Dudek
SGLT-2 inhibition by empagliflozin has no effect on experimental arterial thrombosis in a murine model of low-grade inflammation [0.03%]
恩格列净通过选择性钠葡萄糖协同转运蛋白-2抑制在低度炎症小鼠动脉血栓形成中的作用
Luca Liberale,Simon Kraler,Yustina M Puspitasari et al.
Luca Liberale et al.
Aims: Low-grade inflammation couples dysmetabolic states to insulin resistance and atherosclerotic cardiovascular (CV) disease (ASCVD). Selective sodium-glucose co-transporter 2 (SGLT-2) inhibition by empagliflozin improv...
Randomized Controlled Trial
Cardiovascular research. 2023 May 2;119(3):843-856. DOI:10.1093/cvr/cvac126 2023
Mitochondrial calcium and reactive oxygen species in cardiovascular disease [0.03%]
心血管疾病中的线粒体钙及活性氧物种
Elizabeth Murphy,Julia C Liu
Elizabeth Murphy
Cardiomyocytes are one of the most mitochondria-rich cell types in the body, with ∼30-40% of the cell volume being composed of mitochondria. Mitochondria are well established as the primary site of adenosine triphosphate (ATP) generation i...
The microsomal prostaglandin E synthase-1/prostaglandin E2 axis induces recovery from ischaemia via recruitment of regulatory T cells [0.03%]
微泡前列腺素E合成酶-1/前列腺素E2轴通过募集调节性T细胞促进缺血后的恢复
Hideki Amano,Koji Eshima,Yoshiya Ito et al.
Hideki Amano et al.
Aims: Microsomal prostaglandin E synthase-1 (mPGES-1)/prostaglandin E2 (PGE2) induces angiogenesis through the prostaglandin E2 receptor (EP1-4). Among immune cells, regulatory T cells (Tregs), which inhibit immune respon...
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction [0.03%]
实验性心肌梗死后单核细胞衍生的巨噬细胞多样性的动态变化
Giuseppe Rizzo,Julius Gropper,Marie Piollet et al.
Giuseppe Rizzo et al.
Aims: Macrophages have a critical and dual role in post-ischaemic cardiac repair, as they can foster both tissue healing and damage. Multiple subsets of tissue resident and monocyte-derived macrophages coexist in the infa...
The backstage of the Russian-Ukrainian war: refugees in urgent need of cardiovascular management [0.03%]
俄罗斯乌克兰战事背后的难民急需心血管疾病管理
Bartlomiej Guzik,Anna Bernacik,Anna Pulka et al.
Bartlomiej Guzik et al.
Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans [0.03%]
生热脂肪组织在脂质代谢和动脉粥样硬化心血管疾病中的作用：来自小鼠和人类研究的启示
Zhixiong Ying,Naomi Tramper,Enchen Zhou et al.
Zhixiong Ying et al.
Brown adipocytes within brown adipose tissue (BAT) and beige adipocytes within white adipose tissue dissipate nutritional energy as heat. Studies in mice have shown that activation of thermogenesis in brown and beige adipocytes enhances the...
The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials [0.03%]
益生菌和合生元对心血管代谢危险因素患者血脂参数影响的系统评价和meta分析
Zeinab Ghorbani,Asma Kazemi,Theda U P Bartolomaeus et al.
Zeinab Ghorbani et al.
Although the available evidence emphasizes the beneficial effects of probiotics in normalizing various cardiometabolic markers, there is still substantial uncertainty in this regard. Thus, we set out to determine the effect sizes of probiot...
Meta-Analysis
Cardiovascular research. 2023 May 2;119(4):933-956. DOI:10.1093/cvr/cvac128 2023