Remnant cholesterol reduction for reduction of residual ASCVD risk [0.03%]
残余胆固醇降低与动脉粥样硬化性心血管疾病剩余风险降低的关系研究
Takahito Doi,Karen Hvid,Børge G Nordestgaard
Takahito Doi
NEREA: A versatile computer vision-based software for analyzing angiogenesis [0.03%]
基于计算机视觉的血管生成分析软件NEREA
Nerea Jimenez-Tellez,Alberto Casas-Ortiz,Francesca Vacante et al.
Nerea Jimenez-Tellez et al.
Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF [0.03%]
人类心代谢HFpEF的左心室多组学综合景观
Federico Capone,Karl-Philipp Rommel,Martin Forbes et al.
Federico Capone et al.
Background: Heart failure with preserved ejection fraction (HFpEF), the leading form of heart failure, is burdened by high morbidity and mortality, owing to gaps in our understanding of its molecular and pathophysiologica...
The immunometabolic role of pyruvate dehydrogenase kinase/pyruvate dehydrogenase axis in cardiovascular disease and beyond [0.03%]
丙酮酸脱氢酶激酶/丙酮酸脱氢酶轴在心血管疾病等免疫代谢中的作用
Andrietta Grentzmann,Daniel F J Ketelhuth
Andrietta Grentzmann
The pyruvate dehydrogenase kinase (PDK)/pyruvate dehydrogenase (PDH) axis plays a pivotal role in regulating cellular energy metabolism, controlling the flux between the tricarboxylic acid cycle and oxidative phosphorylation. Traditionally ...
Cell migration inducing protein alleviates adverse remodeling after ischemia and reperfusion injury by controlling fibroblast activation [0.03%]
细胞迁移诱导蛋白通过控制成纤维细胞活化来缓解缺血再灌注损伤后的不良重塑
Schneckmann Rebekka,Hube Theresa,Darakchieva Viktoria et al.
Schneckmann Rebekka et al.
Aims: Myocardial infarction (MI) remains one of the leading causes of mortality and morbidity worldwide. Cardiac remodeling is a key process following MI, involving changes in cellular composition and extracellular matrix...
Inhibition of the PD-1 immune checkpoint and the development of heart failure in the presence of prior cardiac ischemia [0.03%]
PD-1免疫检查点的抑制与既往存在心脏缺血条件下的心力衰竭的发展关系的研究
Tamás G Gergely,Zsófia D Drobni,Tamás Kovács et al.
Tamás G Gergely et al.
Aims: Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment. However, their use often leads to cardiovascular adverse effects, including cardiac dysfunction. Here, we hypothesized that a prior cardiac is...
Annika M T Braun,Alexander Lang,Julian U G Wagner
Annika M T Braun
Aging is the major risk factor for cardiovascular disease, the leading cause of death worldwide. Research on age-related cardiac pathologies has predominantly centered on the left ventricle; however, the atria have been relatively underexpl...
Epitranscriptomic control of VSMC plasticity: Expanding the landscape beyond m6A [0.03%]
血管平滑肌细胞可塑性的表观转录组调控:m6A之外的新视野
Haojie Yu,Yibin Wang
Haojie Yu
Tanveer Tabish,Craig A Lygate
Tanveer Tabish
miR-146a-5p mediates atherogenic signalling from immune to vascular cells [0.03%]
miR-146a-5p介导免疫细胞至血管细胞的动脉粥样硬化信号转导
Montserrat Climent,Stefania Zani,Nicolò Salvarani et al.
Montserrat Climent et al.
Aims: MicroRNAs (miRNAs) regulate gene expression and are involved in various biological processes, including vascular homeostasis. Macrophages (Mϕs) and vascular smooth muscle cells (VSMCs) play key roles in vascular he...