Lipoprotein(a) and calcific aortic valve disease initiation and progression: a systematic review and meta-analysis [0.03%]
脂蛋白(a)与主动脉瓣钙化发病和进展的关系：系统性回顾和meta分析
Panteleimon Pantelidis,Evangelos Oikonomou,Stamatios Lampsas et al.
Panteleimon Pantelidis et al.
Although evidence indicates the association of lipoprotein(a) [Lp(a)] with atherosclerosis, the link with calcific aortic valve disease (CAVD) is unclear. This systematic review and meta-analysis explores the connection between Lp(a) and ao...
Lem2 is essential for cardiac development by maintaining nuclear integrity [0.03%]
Lem2通过维持核完整性在心脏发育中起重要作用
Jacob A Ross,Nathaly Arcos-Villacis,Edmund Battey et al.
Jacob A Ross et al.
Aims: Nuclear envelope integrity is essential for the compartmentalization of the nucleus and cytoplasm. Importantly, mutations in genes encoding nuclear envelope (NE) and associated proteins are the second highest cause ...
CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression [0.03%]
CHD7通过调控SECOND心脏场基因表达的ISL1激活子来参与CHARGE综合症的发生发展
Athanasia Stathopoulou,Ping Wang,Charlotte Thellier et al.
Athanasia Stathopoulou et al.
Aims: Haploinsufficiency of the chromo-domain protein CHD7 underlies most cases of CHARGE syndrome, a multisystem birth defect including congenital heart malformation. Context specific roles for CHD7 in various stem, prog...
The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50+ is mediated by age and biomarkers of cardiovascular disease [0.03%]
年龄和心血管疾病生物标志物介导的肾脏功能、认知功能及社区中50岁及以上人群脑结构异常之间的关联
Natalia Nowak,Celine De Looze,Aisling O&#x;Halloran et al.
Natalia Nowak et al.
Aims: Cognitive impairment has been associated with kidney function and chronic kidney disease. Whether this association is due to accelerated cardiovascular disease (CVD) or an independent specific kidney function effect...
The circadian protein BMAL1 supports endothelial cell cycle during angiogenesis [0.03%]
血管生成过程中昼夜节律蛋白BMAL1支持内皮细胞周期
Matteo Astone,Roxana E Oberkersch,Giovanni Tosi et al.
Matteo Astone et al.
Aims: The circadian clock is an internal biological timer that co-ordinates physiology and gene expression with the 24-h solar day. Circadian clock perturbations have been associated to vascular dysfunctions in mammals, a...
Corticotropin-releasing hormone neurons in the central nucleus of amygdala are required for chronic stress-induced hypertension [0.03%]
中央杏仁核促肾上腺皮质激素释放激素神经元是慢性应激导致高血压的必要条件
Zhao-Fu Sheng,Hua Zhang,Jeffery G Phaup et al.
Zhao-Fu Sheng et al.
Aims: Chronic stress is a well-known risk factor for the development of hypertension. However, the underlying mechanisms remain unclear. Corticotropin-releasing hormone (CRH) neurons in the central nucleus of the amygdala...
Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis [0.03%]
微管正端行走蛋白：新型心钠肽和心律失常调节因子
Gerard A Marchal,Niels Galjart,Vincent Portero et al.
Gerard A Marchal et al.
The cardiac sodium channel NaV1.5 is an essential modulator of cardiac excitability, with decreased NaV1.5 levels at the plasma membrane and consequent reduction in sodium current (INa) leading to potentially lethal cardiac arrhythmias. NaV...
Javier E Sierra-Pagan,Nikita Dsouza,Satyabrata Das et al.
Javier E Sierra-Pagan et al.
Aims: Congenital heart disease (CHD) is the most common genetic birth defect, which has considerable morbidity and mortality. We focused on deciphering key regulators that govern cardiac progenitors and cardiogenesis. FOX...
Smooth muscle cell oligoclonality in vascular disease: same origin, different destinies [0.03%]
平滑肌细胞寡克隆性在血管疾病中具有相同起源但不同命运的现象
Ljubica Matic,Melody Chemaly,Ulf Hedin
Ljubica Matic