Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension [0.03%]
Nedd4-2上调与高血压状态下ACE2泛素化相关性研究
Mazher Mohammed,Blessing Ogunlade,Mona Elgazzaz et al.
Mazher Mohammed et al.
Aims: Angiotensin-converting enzyme 2 (ACE2) is a critical component of the compensatory renin-angiotensin system that is down-regulated during the development of hypertension, possibly via ubiquitination. However, little...
Adele V Ruder,Suzan M W Wetzels,Lieve Temmerman et al.
Adele V Ruder et al.
Monocytes circulate the vasculature at steady state and are recruited to sites of inflammation where they differentiate into macrophages (MФ) to replenish tissue-resident MФ populations and engage in the development of cardiovascular dise...
An interferon gamma response signature links myocardial aging and immunosenescence [0.03%]
一种干扰素γ反应特征模式将心肌衰老和免疫衰老联系在一起
DiyaaElDin Ashour,Sabine Rebs,Panagiota Arampatzi et al.
DiyaaElDin Ashour et al.
Aims: Aging entails profound immunological transformations that can impact myocardial homeostasis and predispose to heart failure. However, preclinical research in the immune-cardiology field is mostly conducted in young ...
The unknown functions of a known protein: the case of coagulation factor XI [0.03%]
一种已知蛋白的未知功能——以凝血因子XI为例
Emiel P C van der Vorst,Lina Badimon
Emiel P C van der Vorst
A novel patient-patient network medicine approach to refine hypertrophic cardiomyopathy subgrouping: implications for risk stratification [0.03%]
一种新颖的患者间网络药物方法：细化肥厚型心肌病亚组分类及其风险分层意义
Rui-Sheng Wang,Ethan J Rowin,Barry J Maron et al.
Rui-Sheng Wang et al.
Prostaglandins bet on regulatory T cells to promote therapeutic revascularization [0.03%]
前列腺素通过促进调节性T细胞的生成来促进治疗性再血管化
Jean-Sébastien Silvestre
Jean-Sébastien Silvestre
Monika M Gladka,Jolanda van der Velden
Monika M Gladka
Challenging the status quo: a case for the lack of gut microbiota exacerbating hypertensive end-organ damage [0.03%]
挑战现状：肠道微生物缺乏加剧高血压靶器官损伤的案例分析
Chudan Xu,Francine Z Marques
Chudan Xu
A machine learning model identifies a functional connectome signature that predicts blood pressure levels: imaging insights from a large population of 35 882 patients [0.03%]
一种机器学习模型识别出可预测血压的功能性连接组标志：来自35882名患者的大规模影像学见解
Roberta Avvisato,Imma Forzano,Fahimeh Varzideh et al.
Roberta Avvisato et al.
Arterial wall inflammation assessed by 18F-FDG-PET/CT is higher in individuals with Type 1 diabetes and associated with circulating inflammatory proteins [0.03%]
1型糖尿病患者动脉壁炎症的18F-FDG-PET / CT评估及其与循环炎性蛋白的关系较高
Anna W M Janssen,Julia I P van Heck,Rinke Stienstra et al.
Anna W M Janssen et al.
Aims: The article investigates whether chronic hyperglycaemia in Type 1 diabetes (T1D) is associated with a proinflammatory immune signature and with arterial wall inflammation, driving the development of atherosclerosis....