Abdominal aortic aneurysms and platelets: infiltration, inflammation, and elastin disintegration [0.03%]
腹主动脉瘤和血小板：浸润、炎症及弹性蛋白解体
Bowen Li,Hong S Lu,Alan Daugherty
Bowen Li
Negative relationship between eicosapentaenoic acid and inflammatory biomarkers in patients with acute myocardial infarction [0.03%]
二十碳五烯酸与急性心肌梗死患者炎症标志物的负相关关系
David Masson,Damien Leleu,Michel Farnier et al.
David Masson et al.
Mitochondrial fatty acid oxidation is the major source of cardiac adenosine triphosphate production in heart failure with preserved ejection fraction [0.03%]
心室射血分数保留的心力衰竭中线粒体脂肪酸氧化是心脏三磷酸腺苷生成的主要来源
Qiuyu Sun,Berna Güven,Cory S Wagg et al.
Qiuyu Sun et al.
Aims: Heart failure with preserved ejection fraction (HFpEF) is a prevalent disease worldwide. While it is well established that alterations of cardiac energy metabolism contribute to cardiovascular pathology, the precise...
Heracles and the Lernaean Hydra: uncovering new layers of transcriptome regulation [0.03%]
赫拉克勒斯与勒纳涅水怪：转录组调控新机制的探索
Giulia Spanò,Selen Pehlivanoğlu,Leon J De Windt
Giulia Spanò
The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology [0.03%]
细胞衰老在与心脏病理相关的促纤维化心房重塑中的作用
Mozhdeh Mehdizadeh,Patrice Naud,Issam H Abu-Taha et al.
Mozhdeh Mehdizadeh et al.
Aims: Cellular senescence is a stress-related or aging response believed to contribute to many cardiac conditions; however, its role in atrial fibrillation (AF) is unknown. Age is the single most important determinant of ...
Peter Seizer,Saskia N I von Ungern-Sternberg,Verena Haug et al.
Peter Seizer et al.
Aims: Cyclophilin A (CyPA) induces leucocyte recruitment and platelet activation upon release into the extracellular space. Extracellular CyPA therefore plays a critical role in immuno-inflammatory responses in tissue inj...
Gene therapy encoding cell cycle factors to treat chronic ischemic heart failure in rats [0.03%]
利用基因疗法编码细胞周期因子治疗大鼠慢性缺血性心力衰竭
Riham R E Abouleisa,Xian-Liang Tang,Qinghui Ou et al.
Riham R E Abouleisa et al.
Aims: Gene therapies to induce cardiomyocyte (CM) cell cycle re-entry have shown a potential to treat subacute ischaemic heart failure (IHF) but have not been tested in the more relevant setting of chronic IHF. Our group ...
IKKβ stabilizes Mitofusin 2 and suppresses doxorubicin cardiomyopathy [0.03%]
IKKβ 稳定线粒体融合蛋白 2 并抑制多柔比星心肌病
Matthew Guberman,Rimpy Dhingra,Jenna Cross et al.
Matthew Guberman et al.
Aims: The mitochondrial dynamics protein Mitofusin 2 (MFN2) coordinates critical cellular processes including mitochondrial bioenergetics, quality control, and cell viability. The NF-κB kinase IKKβ suppresses mitochondr...
Peter Libby,Stephen L Pinkosky,Steven E Nissen
Peter Libby