Understanding and controlling the increasing burden of cardiovascular diseases in Africa [0.03%]
理解并控制非洲日益加重的心血管疾病负担
Paul Olowoyo,Pasquale Maffia,Tomasz J Guzik et al.
Paul Olowoyo et al.
Large animal models of pressure overload-induced cardiac left ventricular hypertrophy to study remodelling of the human heart with aortic stenosis [0.03%]
用于研究主动脉瓣狭窄引起的人心脏重构的大动物压力超负荷心左室肥大的模型
Evangelia Beslika,Adelino Leite-Moreira,Leon J De Windt et al.
Evangelia Beslika et al.
Pathologic cardiac hypertrophy is a common consequence of many cardiovascular diseases, including aortic stenosis (AS). AS is known to increase the pressure load of the left ventricle, causing a compensative response of the cardiac muscle, ...
Bhawana Singh,Manuel Mayr
Bhawana Singh
Jordi Heijman,Corina T Madreiter-Sokolowski
Jordi Heijman
Heart failure-induced microbial dysbiosis contributes to colonic tumour formation in mice [0.03%]
心脏衰竭诱导的小鼠肠道微生物群失调促进了结肠肿瘤的形成
Sanne de Wit,Lotte Geerlings,Canxia Shi et al.
Sanne de Wit et al.
Aims: Heart failure (HF) and cancer are the leading causes of death worldwide. Epidemiological studies revealed that HF patients are prone to develop cancer. Preclinical studies provided some insights into this connection...
Decreasing microtubule detyrosination modulates Nav1.5 subcellular distribution and restores sodium current in mdx cardiomyocytes [0.03%]
减少微管去酪氨酸化可调节Nav1.5亚细胞分布并恢复mdx心肌细胞的钠电流
Giovanna Nasilli,Tanja M de Waal,Gerard A Marchal et al.
Giovanna Nasilli et al.
Aims: The microtubule (MT) network plays a major role in the transport of the cardiac sodium channel Nav1.5 to the membrane, where the latter associates with interacting proteins such as dystrophin. Alterations in MT dyna...
Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with other cardiovascular diseases [0.03%]
高血压中心肌成纤维细胞，基质成纤维细胞和免疫成纤维细胞；与其他心血管疾病的异同点
Keiichi Torimoto,Katherine Elliott,Yuki Nakayama et al.
Keiichi Torimoto et al.
Hypertension is a major cause of cardiovascular diseases such as myocardial infarction and stroke. Cardiovascular fibrosis occurs with hypertension and contributes to vascular resistance, aortic stiffness, and cardiac hypertrophy. However, ...
Atrial fibrillation in the young: consider heritable conditions like short QT syndrome [0.03%]
年轻患者的房颤：要考虑到短QT间期综合征等遗传性疾病的可能性
Larissa Fabritz,Marc D Lemoine
Larissa Fabritz
A new year's resolution to resolve atrial fibrillation: Resolvin D1 emerges as a powerful target against post-MI atrial remodelling [0.03%]
新年决心解决房颤：溶解素D1作为对抗心肌梗死后心脏重塑的强大目标出现
Juan J Velasco,Fadi G Akar
Juan J Velasco
Endothelial to mesenchymal transition: at the axis of cardiovascular health and disease [0.03%]
内皮向间充质转化：心血管疾病与健康转换的轴心
Ignacio Fernando Hall,Franceska Kishta,Yang Xu et al.
Ignacio Fernando Hall et al.
Endothelial cells (ECs) line the luminal surface of blood vessels and play a major role in vascular (patho)-physiology by acting as a barrier, sensing circulating factors and intrinsic/extrinsic signals. ECs have the capacity to undergo end...