Insulin receptors in vascular smooth muscle cells regulate plaque stability of atherosclerosis [0.03%]
血管平滑肌细胞的胰岛素受体调控动脉粥样硬化斑块稳定性
Qian Li,Jialin Fu,Kyoungmin Park et al.
Qian Li et al.
Aims: Increased prevalence of acute myocardial infarction related to diabetes and insulin resistance is associated with an elevated risk of unstable atherosclerotic plaques, which are characterized by reduced vascular smo...
Plasma biomarkers of inflammation associate with blood pressure and arterial stiffness in adolescents after very preterm birth [0.03%]
极低出生体重后青春期炎性生物标志物与血压及动脉僵硬度的关系
Anja Meissner,Jonas Liefke,Frank Matthes et al.
Anja Meissner et al.
Early coronary revascularization among 'stable' patients with non-ST-segment elevation acute coronary syndromes: the role of diabetes and age [0.03%]
非ST段抬高急性冠脉综合征“稳定”患者早期冠状动脉再血管化与糖尿病和年龄的关系
Natalia Fabin,Edina Cenko,Maria Bergami et al.
Natalia Fabin et al.
Aims: To investigate the impact of an early coronary revascularization (65 years) undergoing early revascularization compared to those receiving an initial conservative strategy both in the diabetic (3.3% vs. 6.7%; RR: 0....
Comparative Study
Cardiovascular research. 2024 Dec 14;120(16):2064-2077. DOI:10.1093/cvr/cvae190 2024
Unlocking unknown mutations to understand causal relationships in cardiovascular science: paving the path to personalized cardiovascular care [0.03%]
解锁未知突变以了解心血管科学中的因果关系:迈向个性化心血管护理之路
Soumaya Ben-Aicha,Dorian Haskard
Soumaya Ben-Aicha
Regulation of Ptbp1-controlled alternative splicing of pyruvate kinase muscle by liver kinase B1 governs vascular smooth muscle cell plasticity in vivo [0.03%]
肝激酶B1通过调节Ptbp1控制的丙酮酸激酶肌型向肝型的可变剪接调控血管平滑肌细胞的转分化
Zhaohua Cai,Ganesh Satyanarayana,Ping Song et al.
Zhaohua Cai et al.
Aims: Vascular smooth muscle cell (VSMC) plasticity is a state in which VSMCs undergo phenotypic switching from a quiescent contractile phenotype into other functionally distinct phenotypes. Although emerging evidence sug...
Optical coherence tomography assessment of the impact of colchicine on non-culprit coronary plaque composition after myocardial infarction [0.03%]
氯苯唑胺对心肌梗死患者非罪犯冠状动脉斑块组成的影响的光学相干断层成像评估
Peter J Psaltis,Mau T Nguyen,Kuljit Singh et al.
Peter J Psaltis et al.
Background: Low-dose colchicine reduces the risk of cardiovascular events after myocardial infarction (MI). The purpose of this study was to assess the effect of colchicine post-MI on coronary plaque morphology in non-cul...
Burden of risk factors in women and men with unrecognized myocardial infarction: a systematic review and meta-analysis † [0.03%]
隐匿性心肌梗死患者的风险因素负担:系统评价和meta分析
Julie A E van Oortmerssen,Noluthando Ntlapo,Martijn J Tilly et al.
Julie A E van Oortmerssen et al.
Unrecognized myocardial infarction (MI) is an MI that remains undetected in the acute phase and is associated with an unfavourable prognosis. With this systematic review and meta-analysis, we evaluated the burden of cardiovascular risk fact...
Physiological and pathological ventricular hypertrophy: a role for cavin-2 mediated Akt regulation [0.03%]
腔静脉增生与病理生理学:一种由cavin-2介导的Akt调节的作用
Raffaele Coppini,Lucrezia Giammarino,Elisabetta Cerbai
Raffaele Coppini
Single-cell analysis reveals the implication of vascular endothelial cell-intrinsic ANGPT2 in human intracranial aneurysm [0.03%]
单细胞分析揭示人脑动脉瘤中血管内皮细胞自身ANGPT2的作用
Guo Yu,Jia Li,Hongfei Zhang et al.
Guo Yu et al.
Aims: While previous single-cell RNA sequencing (scRNA-seq) studies have attempted to dissect intracranial aneurysm (IA), the primary molecular mechanism for IA pathogenesis remains unknown. Here, we uncovered the alterat...
The diabetic myocardial transcriptome reveals Erbb3 and Hspa2 as a novel biomarkers of incident heart failure [0.03%]
糖尿病心肌转录组揭示了Erbb3和Hspa2是新发心力衰竭的生物标志物
Marcella S Conning-Rowland,Marilena Giannoudi,Michael Drozd et al.
Marcella S Conning-Rowland et al.
Aims: Diabetes mellitus (DM) increases heart failure incidence and worsens prognosis, but its molecular basis is poorly defined in humans. We aimed to define the diabetic myocardial transcriptome and validate hits in thei...