PIEZO1 regulates smooth muscle cell plasticity by integrating mechanical stretch with glycolytic metabolism [0.03%]
PIEZO1通过整合机械牵拉与糖酵解代谢调控平滑肌细胞的可塑性
Yapeng Cao,Liran Xu,Min Zhang et al.
Yapeng Cao et al.
Aims: Pulmonary artery smooth muscle cells (PASMCs) sense and respond to constant mechanical strain, which is vital for lung homeostasis and disease. Mechanical stimuli and altered glycolytic metabolism are intrinsically ...
Julián Albarrán-Juárez
Julián Albarrán-Juárez
VEGF-C-mediated cardiac lymphangiogenesis promotes inflammation resolution in autoimmune acute myocarditis in mice [0.03%]
小鼠自身免疫性急性心肌炎中,VEGF-C介导的心脏淋巴管生成促进炎症消退
Nanako Nakanishi,Shigeru Hara,Keiki Nagaharu et al.
Nanako Nakanishi et al.
Aims: Acute myocarditis is an immune-mediated inflammatory disease characterized by myocardial inflammation and edema. Although cardiac lymphatic vessels are essential for fluid clearance and immune regulation, their role...
Unravelling mitochondrial succinate transport during I/R and devising a novel transport inhibitor show promise for targeting I/R injury, but will efficacy remain under more human-like conditions present during I/R? [0.03%]
解开线粒体琥珀酸转运在缺血再灌注中的作用,并设计一种新型转运抑制剂,有望针对缺血再灌注损伤进行治疗,但在更接近人类的缺血再灌注条件下,其疗效是否会保持呢?
Qian Wang,Xin Hu,Coert J Zuurbier
Qian Wang
Sodium glucose co-transporter inhibition as a strategy to stabilize the microvasculature in sickle cell disease [0.03%]
在镰状细胞病中利用钠葡萄糖共转运体抑制作用稳定微血管的策略
Muhammad Shahzeb Khan,Muhammad Sameer Arshad,Stefan D Anker
Muhammad Shahzeb Khan
NEWTON-CABG beyond intensive LDL-C lowering: where do we turn to prevent vein graft disease? [0.03%]
新的降低LDL-C水平方法治疗冠状动脉旁路移植术后的血管疾病?
Kapka Miteva,François Mach
Kapka Miteva
Lukas J Weiss,Maria Drayss,David Unsin et al.
Lukas J Weiss et al.
The impact of inflammation, neuromodulation and gut microbiota on developing cardiac fibrosis and hypertension [0.03%]
炎症、神经调节和肠道菌群在心脏纤维化和高血压发生发展中的影响
Michał Kozdrowicki,Piotr Szczepaniak,Vladyslav Kyslyi et al.
Michał Kozdrowicki et al.
Cardiovascular diseases (CVD) are the leading cause of premature mortality worldwide. Due to pressure overload and cardiac fibrosis, CVD often begin with hypertension and gradually progress to heart failure. Cardiac fibrosis reduces the num...
Relationship between body mass index and endogenous fibrinolytic status in 600 patients with ST-elevation myocardial infarction [0.03%]
600例ST段抬高型心肌梗死患者体重指数与体内纤溶状态相关性分析
Joshua H Leader,Gemma Vilahur,Ramzi A Ajjan et al.
Joshua H Leader et al.
Selective targeting of coronary lesions for plaque sealing to prevent adverse events [0.03%]
用于防止不良事件的冠状动脉病变的斑块密封选择性靶向治疗
Keith M Channon
Keith M Channon