Association between BNT162b2 or CoronaVac COVID-19 vaccines and major adverse cardiovascular events among individuals with cardiovascular disease [0.03%]
心血管病患者接种BNT162b2或CoronaVac新冠疫苗后主要心血管不良事件的风险分析
Xuxiao Ye,Tiantian Ma,Joseph E Blais et al.
Xuxiao Ye et al.
Aims: Concern about the cardiovascular safety of coronavirus disease 2019 (COVID-19) vaccines among individuals with cardiovascular disease (CVD) may lead to vaccine hesitancy. We sought to assess the association between ...
Eugene Braunwald,Tomasz J Guzik
Eugene Braunwald
Magdolna Nagy,Hugo Ten Cate
Magdolna Nagy
Impaired regulation of MMP2/16-MLCK3 by miR-146a-5p increased susceptibility to myocardial ischaemic injury in aging mice [0.03%]
miR-146a-5p对MMP2/16-MLCK3调节功能减退致衰老小鼠心肌缺血损伤易感性增加
Ming Dong,Dishen Chen,Yanxia Zhu et al.
Ming Dong et al.
Aims: Aging impairs cardiac function and increases susceptibility to myocardial ischaemic injury. Cardiac myosin light chain kinase (MLCK3) phosphorylates cardiac myosin regulatory light chain (MLC2), controlling sarcomer...
Unc51-like-kinase 1-mediated mitophagy prevents pathological cardiac remodelling and heart failure [0.03%]
Unc51样激酶1介导的线粒体自噬防止心脏重塑和心力衰竭
Rimpy Dhingra,Lorrie A Kirshenbaum
Rimpy Dhingra
Jan Gehlen,Anja Stundl,Radoslaw Debiec et al.
Jan Gehlen et al.
Aims: The present study aims to characterize the genetic risk architecture of bicuspid aortic valve (BAV) disease, the most common congenital heart defect. ...
Initiation of ventricular arrhythmia in the acquired long QT syndrome [0.03%]
获得性长QT综合征的室性心律失常发病机制研究进展
Cherry Alexander,Martin J Bishop,Rebecca J Gilchrist et al.
Cherry Alexander et al.
Aims: Long QT syndrome (LQTS) carries a risk of life-threatening polymorphic ventricular tachycardia (Torsades de Pointes, TdP) and is a major cause of premature sudden cardiac death. TdP is induced by R-on-T premature ve...
Ragini Phansalkar,Kristy Red-Horse
Ragini Phansalkar
Ali J Marian
Ali J Marian
Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study [0.03%]
DNA甲基转移酶SETD7介导的Hippo效应分子YAP甲基化在心肌缺血损伤中的作用及机制研究
Samuele Ambrosini,Fabrizio Montecucco,Detmar Kolijn et al.
Samuele Ambrosini et al.
Aims: Methylation of non-histone proteins is emerging as a central regulatory mechanism in health and disease. The methyltransferase SETD7 has shown to methylate and alter the function of a variety of proteins in vitro; h...