Targeting CD8+ T cells in cardiovascular diseases - current options and therapeutic perspectives [0.03%]
心血管疾病中针对CD8+t细胞的治疗-目前的选择和治疗前景
Rida Al-Rifai,Vincent Duval,Icia Santos-Zas et al.
Rida Al-Rifai et al.
T lymphocytes expressing the CD8 coreceptor, often referred to as cytotoxic T-lymphocytes (CTL), are critical in defending against virus infections and cancers. CD8 encompasses a diverse family of proteins, including homodimers, heterodimer...
Sweeteners: erythritol, xylitol and cardiovascular risk - friend or foe? [0.03%]
甜味剂： erythritol和xylitol与心血管风险有关吗？
Bettina K Wölnerhanssen,Anne Christin Meyer-Gerspach,Arduino Arduini et al.
Bettina K Wölnerhanssen et al.
Hyperglycemia harms vascular health and promotes platelet aggregation. Reducing glucose concentration is crucial, and sugar alcohols may aid this effort. Used for over 50 years in food, cosmetic, and pharmaceutical industries, erythritol an...
Jore Van Wauwe,Hannelore Kemps,Pieter Vrancaert et al.
Jore Van Wauwe et al.
Transcriptional regulation is essential for the development, homeostasis, and function of all organisms. Transcription factors and epigenetic modifiers play an indispensable role by direct or indirect interaction with DNA or chromatin. Alth...
Rare pathogenic variants in G-protein-coupled receptor genes involved in gut-to-host communication are associated with cardiovascular disease risk [0.03%]
与肠道-宿主通讯相关的G蛋白偶联受体基因罕见致病突变与心血管疾病风险相关
Leticia Camargo Tavares,Rikeish R Muralitharan,Matthew Snelson et al.
Leticia Camargo Tavares et al.
Decoding calcific aortic valve disease: is liver X receptor the key to lipid metabolism? [0.03%]
解析主动脉瓣钙化：肝X受体是脂质代谢的关键因素吗？
Adrien Lupieri,Elena Aikawa
Adrien Lupieri
Francesco Ruberto,Roger Foo
Francesco Ruberto
Deficiency of NPR-C triggers high salt-induced thoracic aortic dissection by impairing mitochondrial homeostasis [0.03%]
NPR-C缺乏通过损害线粒体稳态触发高盐诱导的胸主动脉夹层缺陷
Jin-Qiu Wei,Yi Yang,Wen-Hui Zhai et al.
Jin-Qiu Wei et al.
Aims: Thoracic aortic dissection (TAD) is a highly fatal disease lacking effective pharmacologic interventions in clinical practice. Emerging evidence indicates that the natriuretic peptide receptor C (NPR-C) plays a cruc...
Novel roles of Nrf3-Trim5 axis in vascular smooth muscle cell dysfunctions and neointimal hyperplasia [0.03%]
Nrf3-Trim5轴在血管平滑肌细胞功能障碍和内膜增生中的新作用
Qishan Chen,Shasha Sun,Zhenning Shi et al.
Qishan Chen et al.
Aims: Neointimal hyperplasia (NIH) characterized by vascular smooth muscle cell (VSMC) dysfunctions plays a critical role in many vascular diseases including atherosclerosis and restenosis, which leads to serious ischemic...
Robin P Choudhury
Robin P Choudhury
Endothelial IGF-1 signaling: a conductor of vascular barrier function and LDL trafficking in atherogenesis [0.03%]
内皮IGF-1信号传导：在动脉粥样硬化中调控血管屏障功能和LDL转运的指挥者
Cong Liu,Joanna M Kalucka
Cong Liu