Telomere recapping prevents pathogenic telomere-to-mitochondrial DNA communication in heart failure [0.03%]
端粒回覆可防止心力衰竭中端粒与线粒体DNA间的病理性通讯
Yinlong Zhao,Xiaolu Bao,Weiyao Xiong et al.
Yinlong Zhao et al.
Aims: Heart failure (HF) remains a highly prevalent condition with current therapeutic options, five-year survival remains at fifty percent. Diseased cardiomyocytes have been demonstrated to exhibit telomeric shortening a...
Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients [0.03%]
基于深度谱图库的质谱蛋白质组分析揭示持续性心房颤动患者的左右心耳蛋白质组同质化
Aiste Liutkute,Takiy-Eddine Berrandou,Stefanie Kestel et al.
Aiste Liutkute et al.
Aims: Pulmonary veins in the left atrium (LA) are well-established as a critical site for the initiation of atrial fibrillation (AF). Emerging evidence suggests that in persistent AF (persAF), AF triggers may extend beyon...
Bridging the mind-heart gap: depression in CVD clinical practice guidelines [0.03%]
弥合心理与生理的鸿沟：心血管疾病临床指南中的抑郁症条款
Kapka Miteva,François Mach,Aliki Buhayer
Kapka Miteva
Single nucleus RNA sequencing and functional in vivo studies reveal TCF21 as a protective regulator in cardiac fibrosis [0.03%]
单细胞核RNA测序和体内功能研究表明TCF21可防治心肌纤维化
Tousif Azmain,Doan Duy Hai Tran,Afifa Binta Saifuddin et al.
Tousif Azmain et al.
Aims: Cardiac fibrosis remains a significant and currently untreatable contributor to mortality in chronic heart disease. This study aimed to comprehensively map cell-specific pathological changes in fibrotic heart tissue...
Withholding beta-blockers after myocardial infarction: reasons to be cautious [0.03%]
心肌梗死后谨慎停用β受体阻滞剂的理由
John G F Cleland,Ben Hurdus,Chris P Gale
John G F Cleland
Tuning atrial repolarisation by modulation of Kv1.5 channelosome via Lig3-4 proteins [0.03%]
通过Lig3-4蛋白调控Kv1.5通道体以调谐心房复极化
Ursula Ravens,Anthony Cote,Rémi Peyronnet
Ursula Ravens
Endothelial decorin in cardiac ageing: mechanistic ambiguities and therapeutic challenges [0.03%]
心脏衰老中的内皮层网状蛋白：机制模糊性和治疗挑战性
DuJiang Yang,GuoYou Wang
DuJiang Yang
This letter provides a critical analysis of the recent study by Luxán et al. (Cardiovasc Res. 2025) on the role of non-glycanated decorin in cardiac ageing. While acknowledging the importance of their findings, we identify several key area...
Repressive chromatin regulates fibrotic potential through Suv39h1 in the heart [0.03%]
染色质抑制通过心脏中的Suv39h1调节纤维化潜力
Tim Koopmans,Eva van Rooij
Tim Koopmans
Identification of serum biomarkers linking myocardial fibrosis, systolic dysfunction and outcomes in patients with severe aortic stenosis [0.03%]
严重主动脉瓣狭窄患者心肌纤维化、收缩功能障碍与结局的血清生物标志物识别
Svante Gersch,João P Ferreira,Andreas Leha et al.
Svante Gersch et al.
RNA splicing in human cardiomyopathies: shared landscape in diverse pathogenic paths [0.03%]
人类心肌病中的RNA剪接：不同致病途径中共有的景观
Yibin Wang,Woan Ting Tay,Chen Gao
Yibin Wang