Relationship between Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism and the Risk of COVID-19: A Meta-Analysis [0.03%]
ACE插入/删除多态性与COVID-19易感性的关系：一项系统综述和 meta 分析
Hu Luoyi,Pan Yan,Fan Qihong
Hu Luoyi
Introduction: Research shows the correlation between angiotensin-converting enzyme (ACE) deletion and insertion (D/I) polymorphism and COVID-19 risk; yet, conclusive evidence is still lacking. Thus, a meta-analysis of rel...
Timing Matters: Effects of Early and Late Estrogen Replacement Therapy on Glucose Metabolism and Vascular Reactivity in Ovariectomized Aged Wistar Rats [0.03%]
时机的问题：早期和晚期雌激素替代疗法对卵巢切除年长威斯特大鼠葡萄糖代谢和血管反应性的影响
Diana Ramírez-Hernández,Pedro López-Sánchez,Diego Lezama-Martínez et al.
Diana Ramírez-Hernández et al.
Cardiovascular disease incidence increases after menopause due to the loss of estrogen cardioprotective effects. However, there are conflicting data regarding the timing of estrogen therapy (ERT) and its effect on vascular dysfunction assoc...
Genetic Variants Associated with High Susceptibility of Premature Ischemic Stroke [0.03%]
与早发性缺血性卒中高易感性相关的基因变异体
Irma Isordia-Salas,David Santiago-Germán,Rosa María Jiménez-Alvarado et al.
Irma Isordia-Salas et al.
Background: Several polymorphisms had been associated with an increased risk of ischemic stroke, but results are inconclusive. The aim of this study was to examine the association between AGTR1 A1166C and TSP-1 N700S poly...
Renin Trajectories and Outcome in Stable Heart Failure with Reduced Ejection Fraction (HFrEF) on Contemporary Therapy: A Monocentric Study from an Austrian Tertiary Hospital Outpatient Clinic [0.03%]
基于当代疗法的稳定期射血分数降低型心力衰竭（HFrEF）患者肾素轨迹及其结局：奥地利一家三级医院门诊单中心研究
Emilie Han,Suriya Prausmüller,Annika Weidenhammer et al.
Emilie Han et al.
Introduction: The renin-angiotensin system (RAS) is the main target of neurohumoral therapy in heart failure with reduced ejection fraction (HFrEF) effectively reducing mortality. Reasonably, renin might serve as a biomar...
New Viral Diseases and New Possible Remedies by Means of the Pharmacology of the Renin-Angiotensin System [0.03%]
新的病毒性疾病及利用肾素-血管紧张素系统药物学的可能治疗方法
Giovanni Sansoè,Manuela Aragno
Giovanni Sansoè
All strains of SARS-CoV-2, as well as previously described SARS-CoV and MERS-CoV, bind to ACE2, the cell membrane receptor of β-coronaviruses. Monocarboxypeptidase ACE2 activity stops upon viral entry into cells, leading to inadequate tiss...
Angiotensin-Converting Enzyme and Hypertension: A Systemic Analysis of Various ACE Inhibitors, Their Side Effects, and Bioactive Peptides as a Putative Therapy for Hypertension [0.03%]
血管紧张素转换酶与高血压：各种血管紧张素转化酶抑制剂及其副作用的系统分析，以及活性多肽作为潜在的降压治疗方案的研究
Hafiz Ahmad,Huma Khan,Shabirul Haque et al.
Hafiz Ahmad et al.
Hypertension is a major risk factor for heart attack, produce atherosclerosis (hardening of the arteries), congestive heart failure, stroke, kidney infection, blindness, end-stage renal infection, and cardiovascular diseases. Many mechanism...
Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism [0.03%]
单侧肾上腺切除术后原发性醛固酮增多症的确认试验生化评估
Shingo Murasawa,Kazunori Kageyama,Mari Usutani et al.
Shingo Murasawa et al.
Primary aldosteronism (PA) is the most common cause of endocrine hypertension. Unilateral PA can be cured using unilateral adrenalectomy (Adx). PA surgery outcome (PASO) criteria, which include clinical and biochemical outcomes, have been p...
Association between Interactions among ACE Gene Polymorphisms and Essential Hypertension in Patients in the Hefei Region, Anhui, China [0.03%]
安徽省合肥市ACE基因多态性交互作用与高血压的相关性研究
Li Wang,Ting-Ting Song,Chang-Wu Dong
Li Wang
Objective: Essential hypertension (EH) is a common cardiovascular disease that endangers human health. Its pathogenesis is complex and has not been fully elucidated. We explore the association between EH and interactions ...
Single Nucleotide Variants (SNVs) of Angiotensin-Converting Enzymes (ACE1 and ACE2): A Plausible Explanation for the Global Variation in COVID-19 Prevalence [0.03%]
血管紧张素转化酶（ACE1和ACE2）的单核苷酸变异(SNVs)：对全球COVID-19流行率差异的一种可能解释
Saad Mahjub Atiku,Dennis Kasozi,Katrina Campbell
Saad Mahjub Atiku
Background: Although it is common knowledge that the coronavirus disease of 2019 (COVID-19) and other viral infections have an uneven impact globally, the reasons for this are still indistinct. The absence of equivalent c...
Hyperoside Ameliorates Renal Tubular Oxidative Damage and Calcium Oxalate Deposition in Rats through AMPK/Nrf2 Signaling Axis [0.03%]
hyperoside通过AMPK/Nrf2信号轴改善大鼠肾小管氧化损伤和草酸钙沉积
Hongyang Tian,Qi Liang,Zhen Shi et al.
Hongyang Tian et al.
Background: Nephrolithiasis is a common disease that seriously affects the health and life quality of patients. Despite the reported effect of hyperoside (Hyp) against nephrolithiasis, the specific mechanism has not been ...