Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes [0.03%]
肠道微生物组的调节特性对糖尿病的发展和治疗的影响
Joann Romano-Keeler,Jöern-Hendrik Weitkamp,Daniel J Moore
Joann Romano-Keeler
Purpose of review: The microbiome continues to demonstrate an important role in immune and metabolic programming. This review will focus on the mechanistic implications of recent findings for diabetes pathogenesis and tre...
Samir Malkani,Taniya DeSilva
Samir Malkani
Purpose of review: To evaluate the controversial aspects of diabetes diagnosis. Recent findings: Within the past 2 years, revised guide...
Closed-loop artificial pancreas: current studies and promise for the future [0.03%]
闭环人工胰腺：当前研究及其未来前景
Stuart A Weinzimer
Stuart A Weinzimer
Purpose of review: The availability of glucose sensors and insulin pumps has enabled the development of devices and software to partially or completely automate insulin delivery. Over the last 2 years, the number of cente...
Olga T Hardy,Michael P Czech,Silvia Corvera
Olga T Hardy
Purpose of review: The association between obesity and insulin resistance is an area of much interest and enormous public health impact, with hundreds of articles being published in the last year focused on the possible m...
Scott M Gordon,William S Davidson
Scott M Gordon
Purpose of review: To review recently published advances in the development of apolipoprotein A-I (apoA-I) mimetic peptides as a potential treatment for cardiovascular diseases. ...
Kendall F Moseley
Kendall F Moseley
Purpose of review: To discuss current literature and hypotheses pertaining to the pathophysiology of increased bone fragility and fracture in men and women with type 2 diabetes mellitus. ...
Early steps in reverse cholesterol transport: cholesteryl ester hydrolase and other hydrolases [0.03%]
反向胆固醇运输的早期步骤：胆甾醇酯水解酶及其他水解酶
Shobha Ghosh
Shobha Ghosh
Purpose of review: Several controversies exist related to the molecular identity and subcellular localization of the enzyme catalyzing macrophage cholesteryl ester hydrolysis. Some of these issues have been reviewed earli...
David W Lam,Derek LeRoith
David W Lam
Purpose of review: An overview of the global epidemic of diabetes and its impact on the understanding of the disease. Recent findings: ...
Scavenger receptor class B type 1 gene polymorphisms and female fertility [0.03%]
清道夫受体B类I基因多态性与女性生育力关系的研究
Mindy S Christianson,Melissa Yates
Mindy S Christianson
Purpose of review: Multiple studies have demonstrated a role for scavenger receptor class B type 1 (SR-B1) in female fertility. Recent studies have implicated specific SR-B1 gene polymorphisms in decreased progesterone pr...
Microvesicles: potential markers and mediators of endothelial dysfunction [0.03%]
微囊泡：内皮细胞功能障碍的潜在标志物和介导因素
Ming-Lin Liu,Kevin Jon Williams
Ming-Lin Liu
Purpose of review: Microvesicles (also known as microparticles) are small membranous structures that are released from platelets and cells upon activation or during apoptosis. Microvesicles have been found in blood, urine...