Somatostatin analogs as a first-line treatment in acromegaly: when is it appropriate? [0.03%]
生长激素瘤的一线治疗还能是生长抑素类似物吗？什么情况下适合使用？
Ludovica F S Grasso,Rosario Pivonello,Annamaria Colao
Ludovica F S Grasso
Purpose of review: To discuss the role of medical therapy of acromegaly as a first-line treatment, focusing on recent data on the use of somatostatin analogs (SSAs), the first-choice pharmacotherapy for treating acromegal...
Steve Rostad
Steve Rostad
Purpose of review: To describe the recent efforts to understand the molecular and genetic mechanisms involved in the tumorigenesis of pituitary adenomas. ...
Testing for growth hormone deficiency in adults: doing without growth hormone-releasing hormone [0.03%]
不用生长激素释放激素试验的成人生长激素缺乏检查法
Atil Y Kargi,George R Merriam
Atil Y Kargi
Purpose of review: This article summarizes recent advances in testing for growth hormone deficiency (GHD) in adults, focusing on critical appraisal of existing growth hormone (GH) provocative tests as well as newer tests ...
John D Carmichael
John D Carmichael
Purpose of review: To discuss the multiple forms of hypophysitis, the various methods of classification, the recent findings in pituitary autoimmunity and novel methods of treating resistant or recurrent hypophysitis. (Ja...
The use of the glucocorticoid receptor antagonist mifepristone in Cushing's syndrome [0.03%]
米非司酮在库欣综合征中的应用
Frederic Castinetti,Thierry Brue,Bernard Conte-Devolx
Frederic Castinetti
Purpose of review: Mifepristone is the first and only available glucocorticoid receptor antagonist. Cushing's syndrome is a rare disease, responsible for increased morbidity and mortality. The treatment of Cushing's syndr...
Evolving utility of sex hormone-binding globulin measurements in clinical medicine [0.03%]
临床医学中性激素结合球蛋白检测的运用及其发展变化趋势
Geoffrey L Hammond,Tsung-Sheng Wu,Marc Simard
Geoffrey L Hammond
Purpose of review: Sex hormone-binding globulin (SHBG) regulates the plasma levels and biological actions of the sex steroids: testosterone and estradiol. Advances in our understanding of how plasma SHBG levels are determ...
Ellen W Seely
Ellen W Seely
David E Schteingart
David E Schteingart
Purpose of review: To describe the significance of a common adrenal radiological finding on computed tomography or MRI. Recent findings: ...
Helena E Virtanen,Sergey Sadov,Jorma Toppari
Helena E Virtanen
Purpose of review: To assess whether prenatal exposure to smoking is associated with impaired reproductive health in exposed men. Recent findings: ...