Michael B Zimmermann,Maria Andersson
Michael B Zimmermann
Purpose of review: Salt iodization has been introduced in many countries to control iodine deficiency. The two most commonly used approaches to assessing iodine nutrition on the population level are estimation of the hous...
Angela M Leung,Lewis E Braverman
Angela M Leung
Purpose of review: To summarize the mechanisms of iodine-induced hypothyroidism and hyperthyroidism, identify the risk factors for thyroid dysfunction following an iodine load, and summarize the major sources of excess io...
Daniel Glinoer,David S Cooper
Daniel Glinoer
Purpose of review: To bring to the attention of healthcare professionals the additional information on propylthiouracil (PTU)-related hepatotoxicity, based on a reanalysis of medical files reported to the Food and Drug Ad...
A rationale for multidisciplinary care in treating neuroendocrine tumours [0.03%]
神经内分泌肿瘤治疗中多学科协作的必要性
David C Metz,Junsung Choi,Jonathan Strosberg et al.
David C Metz et al.
Purpose of review: Disease heterogeneity and multisystem complications represent challenges to the diagnosis and management of neuroendocrine tumours (NET), with the disease often remaining undiagnosed for years after ini...
A role for tolerogenic dendritic cell-induced B-regulatory cells in type 1 diabetes mellitus [0.03%]
耐受性树突状细胞诱导的B-调节细胞在1型糖尿病中的作用
Nick Giannoukakis,Massimo Trucco
Nick Giannoukakis
Purpose of review: To review the important recent findings on the nature, characteristics and function of novel populations of immunosuppressive B-lymphocytes (Bregs) and their possible role as a regulatory cell populatio...
Grant Morahan
Grant Morahan
Purpose of review: Recent identification of over 60 loci contributing to the susceptibility of developing type 1 diabetes (T1D) provides a timely opportunity to assess what is currently known of the genetics of T1D, and w...
Yuxia Zhang,Esther Bandala-Sanchez,Leonard C Harrison
Yuxia Zhang
Purpose of review: Regulatory T cells (Treg) maintain immune homeostasis and prevent autoimmune disease. This review summarizes the recent advances in Treg knowledge relevant to type 1 diabetes, focusing on Treg signature...
Kara Mizokami-Stout,Melanie Cree-Green,Kristen J Nadeau
Kara Mizokami-Stout
Purpose of review: This review focuses on recent literature on insulin resistance in youth with type 2 diabetes mellitus (T2DM). Insulin resistance is associated with a variety of cardiometabolic problems leading to incre...
Ronald G Gill,Nicholas H Bishop
Ronald G Gill
Purpose of review: The dramatic results of the Edmonton Protocol in 2000 triggered tremendous excitement over the application of pancreatic islet transplantation as a viable approach to achieving consistent insulin indepe...