Perspectives on early health economic evaluations of RNA therapies targeted at lipoprotein(a) [0.03%]
针对脂蛋白(a)的RNA疗法早期卫生经济学评估的观点
Angela Burvill,Gerald F Watts,Zanfina Ademi
Angela Burvill
Purpose of review: Early health economic evaluations of new medications are useful, as they consider the implications for health services.We reviewed recent literature on expected clinical outcomes of lowering of elevated...
An overview of persistent chylomicronemia: much more than meets the eye [0.03%]
持久性乳糜微粒血症概述——远不止所见的那样
Miriam Larouche,Gerald F Watts,Christie Ballantyne et al.
Miriam Larouche et al.
Purpose of review: The aim of this review is to provide an overview of severe hypertriglyceridemia presenting in the form of chylomicronemia that persists despite treatment of secondary causes and the use of conventional ...
Psychological determinants and evidence-based behavior change interventions in adherence to therapy for familial hypercholesterolemia [0.03%]
家族性高胆固醇血症治疗中的心理决定因素及基于证据的行为改变干预措施
Martin S Hagger,Kyra Hamilton
Martin S Hagger
Purpose of review: Patients with familial hypercholesterolemia have an elevated risk of premature atherosclerotic cardiovascular disease. Risks can be minimized through pharmacological and 'lifestyle' behavioral (low fat ...
Georgia Rigas,Shirley Alexander,Cilla J Haywood
Georgia Rigas
Purpose of review: Obesity is recognized as a "gateway" chronic, progressive disease of dysfunctional adipocytes. Glucagon-like peptide-1 receptor agonist-based therapies (GLP1BTs), including glucagon-like peptide-1 recep...
Overview of diabetes agents in cardiovascular disease: it takes an orchestra to play Tchaikovsky in symphony [0.03%]
心血管疾病的糖尿病药物概览——交响乐奏鸣曲需要一个乐队齐心协力
Wann Jia Loh
Wann Jia Loh
Purpose of review: The aim of this review was to discuss the use and concerns of diabetes agents, clinical targets, and key aspects to be considered in the management of patients with type 2 diabetes mellitus (T2DM), and ...
Leong Tung Ong,Ching-Hui Sia
Leong Tung Ong
Purpose of review: The heart - brain axis (HBA) is the physiological interactions between the cardiovascular and nervous systems through autonomic nerves, hormones, and cytokines. Patients diagnosed with diabetes mellitus...
Jeyakantha Ratnasingam,Quan Hziung Lim,Siew Pheng Chan
Jeyakantha Ratnasingam
Purpose of review: The aim of this article was to review the up-to-date evidence with regards to the unique features of the Type 2 diabetes (T2D) pathophysiology, complications, response to therapy with the possibility of...
Si Hua Clara Tan,Wann Jia Loh,Su Chi Lim
Si Hua Clara Tan
Purpose of review: This review highlights emerging evidence supporting the premise of precision diabetes care including but not limited to monogenic diabetes and discuss potential opportunities, challenges, and limitation...