Biomarkers and therapies to target endothelial dysfunction in type 2 diabetes: moving a step forward [0.03%]
迈向糖尿病血管病变治疗新途径——针对内皮细胞功能障碍的生物标志物和靶向治疗研究
Ying Jie Chee,Wann Jia Loh,Rinkoo Dalan
Ying Jie Chee
Purpose of review: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality in people with type 2 diabetes mellitus (T2DM). Endothelial dysfunction is a precursor of atherosclerosis. This is a sile...
Adjunctive diabetes therapies and cardiovascular protection in type 1 diabetes: tackling the challenging Tchaikovsky piece [0.03%]
1型糖尿病的辅助降糖治疗与心血管保护：攻克挑战性的柴可夫斯基作品
Wei Ting Wang,Wann Jia Loh
Wei Ting Wang
Purpose of review: This review aims to discuss the cardiometabolic-renal-glycaemic effects of adjunctive diabetes agents in the management of type 1 diabetes. ...
Rashi Agrawal,Tejal Lathia
Rashi Agrawal
Purpose of review: Obesity during pregnancy is a growing global health concern with implications for maternal, fetal, and intergenerational outcomes. This review highlights pathophysiological mechanisms, clinical risks, a...
Akhila Bhandarkar,Sowrabha Bhat,Nitin Kapoor
Akhila Bhandarkar
Purpose of review: Obesity is present in up to 85% of individuals with type 2 diabetes mellitus (T2DM) and poses a major therapeutic challenge. Glucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for...
Khushboo Agarwal,Lakshmi Nagendra,Saptarshi Bhattacharya
Khushboo Agarwal
Purpose of review: Premenopausal osteoporosis, characterized by low bone mass and fractures, is rare but poses long-term skeletal risks. Unlike postmenopausal osteoporosis, it often stems from inadequate peak bone mass ac...
Emerging concepts in the diagnosis and management of metabolically associated steatotic liver disease [0.03%]
代谢相关脂肪性肝病的诊断和管理新概念
Sambit Das,Khushboo Agarwal,Nitin Kapoor et al.
Sambit Das et al.
Purpose of review: Given the global rise of MASLD, which impacts approximately one-third of the population, there is a need for earlier diagnosis and effective treatment strategies to avoid long-term hepatic cardiovascula...
Saumya Sunny,Kathryn Graham,Julie Hephzibah et al.
Saumya Sunny et al.
Purpose of review: The aim of radioactive iodine (RAI) in differentiated thyroid cancer (DTC) is ablation of thyroid remnant and/or treatment of residual disease. This review compares guidelines recommending the use of RA...
Simran Thakkar,Ponnusamy Saravanan,Lakshmi Nagendra et al.
Simran Thakkar et al.
Purpose of review: Early gestational diabetes mellitus (eGDM) is being increasingly detected on the background of rising obesity rates and widespread early pregnancy screening. However, diagnostic criteria and management ...
Obesity-related glomerulopathy: a lesser known complication of obesity [0.03%]
肥胖相关性肾小球病变：一个鲜为人知的肥胖并发症
Sourabh Sharma,Alok Sharma,Nitin Kapoor et al.
Sourabh Sharma et al.
Purpose of review: Obesity is a global health concern and is intricately linked to cardiovascular disease and metabolic disorders. While its causal association with chronic kidney disease (CKD) has also been recognized, t...
Suganya Sekar,Deepak Thomas Abraham
Suganya Sekar
Purpose of review: To review the current medical evidence in the diagnosis and management of thyroid nodules. Recent findings: The wide...