Setmelanotide: a promising advancement for pediatric patients with rare forms of genetic obesity [0.03%]
Setmelanotide：一种针对罕见遗传性肥胖患者的有前景的治疗方法
Christine M Trapp,Marisa Censani
Christine M Trapp
Purpose of review: Examine Setmelanotide use in patients with rare genetic variants that disrupt the melanocortin pathway. Recent findings: ...
Can remnant cholesterol (triglyceride-rich lipoproteins) reclassify estimated risk of atherosclerotic cardiovascular disease? [0.03%]
残余胆固醇（甘油三酯丰富的脂蛋白）能否重新评估动脉粥样硬化性心血管疾病的估计风险？
Takahito Doi,Børge G Nordestgaard,Anne Langsted
Takahito Doi
Purpose of review: To summarize recent studies analyzing reclassification of estimated risk of myocardial infarction (MI) and ischemic heart disease (IHD) by inclusion of remnant cholesterol (= cholesterol content in trig...
Low-carbohydrate diets in type 1 diabetes: balancing benefits and risks [0.03%]
I型糖尿病中的低碳水化合物饮食：权衡利弊
Michael Hancock,Kharis Burns,Seng Khee Gan et al.
Michael Hancock et al.
Purpose of review: Interest in the use of calorie restriction with low-carbohydrate diets for patients with type 1 diabetes appears to be increasing despite physicians' discomfort about its longer term outcomes. A diverge...
Wann Jia Loh,Gerald F Watts
Wann Jia Loh
Purpose of review: The aim of this study was to assess the potential value of the measurement of plasma xenosterols (or phytosterols) concentrations in clinical practice. ...
Eicosapentaenoic acid vs. docosahexaenoic acid for the prevention of cardiovascular disease [0.03%]
二十碳五烯酸与二十二碳六烯酸在心血管疾病预防中的应用比较研究
Ty E Sweeney,Sean P Gaine,Erin D Michos
Ty E Sweeney
Purpose of review: Populations with greater fatty fish intake have lower risk of coronary heart disease. However, trials testing omega-3 fatty acids (FA) on cardiovascular outcomes have yielded inconsistent results. In th...
Nidhi Bansal,Seema Kumar,Preneet Cheema Brar
Nidhi Bansal
Purpose of review: Atherosclerosis and associated cardiovascular risk factors originate in childhood; hence, early management of dyslipidaemia is vital. However, hypercholesterolemia remains untreated or undertreated in m...
Utilizing type 2 diabetes medications outside glycemic parameters - where are we headed? [0.03%]
二型糖尿病药物在糖代谢参数之外的应用-我们正在走向何方？
Natasha Prakash Malkani,Vanita R Aroda
Natasha Prakash Malkani
Purpose of review: Glucose-lowering medications have become strong choices for purposes beyond glucose control in both patients with and without type 2 diabetes. Recent studies have explored the use of specific glucose-lo...
A short history of saturated fat: the making and unmaking of a scientific consensus [0.03%]
饱和脂肪的简史：科学共识的形成与破除
Nina Teicholz
Nina Teicholz
Purpose of review: This article recounts the history of the diet-heart hypothesis from the late 1950s up to the current day, with revelations that have never before been published in the scientific literature. Insights in...
Jeremy Pomeroy,Kelsi-Marie Offenwanger,Tammi Timmler
Jeremy Pomeroy
Purpose of review: Bardet Biedl syndrome (BBS) is a rare disease characterized by obesity and hyperphagia. Despite the very high prevalence of paediatric and adult obesity in this population, the prevalence of diabetes me...