Ana Carolina Vieira Selva,Pushpa Suriyaarachchi,Gustavo Duque
Ana Carolina Vieira Selva
Purpose of review: Sarcopenia is a progressive, multifactorial geriatric syndrome linked to increased risk of falls, fractures, disability, frailty, and all-cause mortality. The pathophysiology of this complex syndrome re...
Normocalcemic primary hyperparathyroidism: an update on diagnostic and management challenges [0.03%]
Krupa B Doshi,Manju Chandran
Krupa B Doshi
Purpose of review: Normocalcemic primary hyperparathyroidism (NPHPT) is defined by persistently elevated parathyroid hormone (PTH) levels in the presence of normal total and ionized serum calcium after excluding secondary...
Prediabetes before pregnancy: implications for risk stratification and research [0.03%]
孕前糖尿病前期：风险分层和研究的启示
Saptarshi Bhattacharya,Viswanathan Mohan,Lakshmi Nagendra et al.
Saptarshi Bhattacharya et al.
Purpose of review: This review evaluates whether pregestational prediabetes identifies women at risk of subsequent gestational diabetes mellitus (GDM) and examines its association with maternal and offspring outcomes. ...
Secondary hyperparathyroidism in chronic kidney disease: update on pathophysiology and new treatment targets [0.03%]
慢性肾脏病继发性甲状旁腺功能亢进症的发病机制及新的治疗靶点更新
Amal Derai,Ditte Hansen,Hanne Skou Jørgensen
Amal Derai
Purpose of review: Secondary hyperparathyroidism remains a universal complication of chronic kidney disease (CKD), yet evidence-based treatment targets for parathyroid hormone (PTH) are lacking. This review revisits the p...
Revisiting the relationship between weight loss and bone health in people living with obesity: insights from the latest evidence [0.03%]
肥胖人群体重减轻与骨健康关系的再审视：最新证据带来的启示
Julien Paccou
Julien Paccou
Purpose of review: This review summarizes recent advances in understanding bone outcomes associated with lifestyle, surgical, and pharmacological weight-loss strategies. ...
Parathyroid hormone assays in 2026: second versus third generation, standardization, and clinical interpretation [0.03%]
2026年甲状旁腺激素检测：第二代与第三代、标准化以及临床解读
Niklas Rye Jørgensen,Etienne Cavalier,Samuel D Vasikaran
Niklas Rye Jørgensen
Purpose of review: Accurate measurement of parathyroid hormone (PTH) remains essential for the diagnosis and management of disorders of mineral metabolism, particularly in parathyroid disorders including in chronic kidney...
Metabolic dysfunction and the use of adjunct medications in type 1 diabetes [0.03%]
1型糖尿病代谢紊乱及联合用药状况分析
Andrew Luk,Yee Seun Cheah,Shivani Misra et al.
Andrew Luk et al.
Purpose of review: Type 1 diabetes is increasingly complicated by obesity and broader metabolic dysfunction, yet there are barriers to the use of adjunctive pharmacotherapies in this population. This review evaluates the ...
Microbiome-derived signaling molecules and the brain-gut axis: emerging mechanisms and clinical implications [0.03%]
源自微生物组的信号分子与脑-肠轴：新兴机制及临床意义
Marya Pulaski,H Christian Weber
Marya Pulaski
Purpose of review: Recent advances in metabolomics, multi-omics integration, and neurogastroenterology have fundamentally reshaped understanding of the human gut microbiome. Rather than microbial composition alone, emergi...
Gerald F Watts,Dick C Chan
Gerald F Watts