Microwave synthesis, crystal structure, antioxidant, and antimicrobial study of new 6-heptyl-5,6-dihydrobenzo[4,5]imidazo[1,2-c]quinazoline compound [0.03%]
微波合成、晶体结构、抗氧化及抗菌研究新的6-庚基-5,6-二氢苯并[4,5]咪唑并[1,2-c]喹唑啉化合物
Hiba Ali Hasan,Emilia Abdulmalek,Mohd Basyaruddin Abdul Rahman et al.
Hiba Ali Hasan et al.
Background: Although the development of antibiotic and antioxidant manufacturing, the problem of bacterial resistance and food and/or cosmetics oxidation still needs more efforts to design new derivatives which can help t...
Determination of antioxidant and antimicrobial activities of the extracts of aerial parts of Portulaca quadrifida [0.03%]
_PORTULACA QUADRIFOIDA_地上部提取物抗氧化及抑菌活性研究
Zelalem Yibralign Desta,Desie Alemaw Cherie
Zelalem Yibralign Desta
Background: The extracts from the aerial parts of Portulaca quadrifida have been reported to show the total flavonoid content, antioxidant and antibacterial activities. ...
Design, synthesis and therapeutic potential of 3-(2-(1H-benzo[d]imidazol-2-ylthio)acetamido)-N-(substituted phenyl)benzamide analogues [0.03%]
3-(2-(1H-苯并咪唑-2-基硫代)乙酰胺基)-N-(取代的苯基)苯甲酰胺类似物的设计、合成及治疗潜力研究
Sumit Tahlan,Kalavathy Ramasamy,Siong Meng Lim et al.
Sumit Tahlan et al.
Background: The emergence of bacterial resistance is a major public health problem. It is essential to develop and synthesize new therapeutic agents with better activity. The mode of actions of certain newly developed ant...
Kevin McAdam,Trevor Enos,Carol Goss et al.
Kevin McAdam et al.
Differences in health risks between different styles of smokeless tobacco products (STPs) have prompted interest in their relative levels of toxic chemicals. We report here the development of methods for the analysis of STPs for coumarin an...
Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies [0.03%]
新型PPARγ激动剂噻唑烷二酮类化合物：分子设计、合成、葡萄糖摄取活性及三维定量构效关系研究
Subhankar P Mandal,Aakriti Garg,P Prabitha et al.
Subhankar P Mandal et al.
Background: An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In...
Development of a practical synthesis of etravirine via a microwave-promoted amination [0.03%]
通过微波促进的胺化反应实用合成埃替拉韦的研究开发
Da Feng,Fenju Wei,Zhao Wang et al.
Da Feng et al.
Background: Etravirine (ETV) was approved as the second generation drug for use in individuals infected with HIV-1 in 2008 by the U.S. FDA with its unique antiviral activity, high specificity, and low toxicity. However, t...
Ligand exchange method for determination of mole ratios of relatively weak metal complexes: a comparative study [0.03%]
相对弱金属配位化合物摩尔比的配体交换测定法：比较研究
Mokhtar Mabrouk,Sherin F Hammad,Mohamed A Abdelaziz et al.
Mokhtar Mabrouk et al.
Ligand exchange method is introduced as an alternative to Job's and mole ratio methods for studying the stoichiometry of relatively weak metal complexes in solutions. The method involves adding varying amounts of a ligand (L) to an excess c...
Synthesis, biological evaluation and molecular docking studies of 6-(4-nitrophenoxy)-1H-imidazo[4,5-b]pyridine derivatives as novel antitubercular agents: future DprE1 inhibitors [0.03%]
作为新型抗结核药物的6-（4-硝基苯氧基）-1H-咪唑并[4,5-b]吡啶衍生物的合成、生物活性评价及分子对接研究：未来的DprE1抑制剂
Jineetkumar Gawad,Chandrakant Bonde
Jineetkumar Gawad
Tuberculosis is an air-borne disease, mostly affecting young adults in their productive years. Here, Ligand-based drug design approach yielded a series of 23 novel 6-(4-nitrophenoxy)-1H-imidazo[4,5-b]pyridine derivatives. The required build...
Classification of different pineapple varieties grown in Malaysia based on volatile fingerprinting and sensory analysis [0.03%]
基于挥发性指纹和感官分析的马来西亚菠萝品种分类
Ola Lasekan,Fatma Khalifa Hussein
Ola Lasekan
Background: Pineapple is highly relished for its attractive sweet flavour and it is widely consumed in both fresh and canned forms. Pineapple flavour is a blend of a number of volatile and non-volatile compounds that are ...
Rashmi Shah,Prabhakar Kumar Verma
Rashmi Shah
Thiophene and its substituted derivatives are very important class of heterocyclic compounds which shows interesting applications in the field of medicinal chemistry. It has made an indispensable anchor for medicinal chemists to produce com...