Comprehensive analysis of anoikis-related lncRNAs for predicting prognosis and response of immunotherapy in hepatocellular carcinoma [0.03%]
全面分析与anoikis相关的长链非编码RNA以预测肝细胞癌的预后和免疫治疗反应
Sihao Du,Ke Cao,Zhenshun Wang et al.
Sihao Du et al.
Nowadays, primary liver cancer is still a major threat to human health. Anoikis is a particular form of programed cell death that has an inhibitory effect on neoplasm metastasis. Although several prognostic models based on anoikis-related g...
Cuproptosis-related lncRNAs are correlated with tumour metabolism and immune microenvironment and predict prognosis in pancreatic cancer patients [0.03%]
与铜死亡相关长链非编码RNA与肿瘤代谢和免疫微环境相关并可预测胰腺癌患者的预后
Yanling Wang,Weiyu Ge,Shengbai Xue et al.
Yanling Wang et al.
Cuproptosis is a novel cell death pathway, and the regulatory mechanism in pancreatic cancer (PC) is unclear. The authors aimed to figure out whether cuproptosis-related lncRNAs (CRLs) could predict prognosis in PC and the underlying mechan...
A comprehensive analysis of FBN2 in bladder cancer: A risk factor and the tumour microenvironment influencer [0.03%]
FBN2在膀胱癌中的综合分析：一个危险因素和肿瘤微环境的影响者
Zechao Lu,Zeguang Lu,Yongchang Lai et al.
Zechao Lu et al.
Bladder cancer (BLCA) is a common and difficult-to-manage disease worldwide. Most common type of BLCA is urothelial carcinoma (UC). Fibrillin 2 (FBN2) was first discovered while studying Marfan syndrome, and its encoded products are associa...
Identification of genomic biomarkers and their pathway crosstalks for deciphering mechanistic links in glioblastoma [0.03%]
鉴定胶质母细胞瘤的基因组生物标志物及其通路相互作用以解读其机制联系
Darrak Moin Quddusi,Naim Bajcinca
Darrak Moin Quddusi
Glioblastoma is a grade IV pernicious neoplasm occurring in the supratentorial region of brain. As its causes are largely unknown, it is essential to understand its dynamics at the molecular level. This necessitates the identification of be...
Chromosome instability-associated prognostic signature and cluster investigation for cutaneous melanoma cases [0.03%]
与皮肤黑色素瘤预后标志和聚类相关的染色体不稳定性研究
Ning Liu,Guangjing Liu,Qian Ma et al.
Ning Liu et al.
Chromosomal instability (CIN) is closely associated to the early detection of several clinical tumours. In this study, the authors first established a novel prognostic model of melanoma using the hub genes of CIN, based on the datasets of T...
Hub genes and pathways in gastric cancer: A comparison between studies that used normal tissues adjacent to the tumour and studies that used healthy tissues as calibrator [0.03%]
胃癌中的中心基因和通路：使用肿瘤相邻的正常组织的研究与使用健康组织作为参照物的研究之间的比较
Khadijeh Sadegh,Amirhossein Ahmadi
Khadijeh Sadegh
Several bioinformatics studies have been performed on high-throughput expression data to determine the cellular pathways and hub genes affected by Gastric cancer (GC). However, these studies differ in using a healthy tissue or normal tissue...
Fusion of various optimisation based feature smoothing methods for wearable and non-invasive blood glucose estimation [0.03%]
基于优化的特征平滑方法融合用于可穿戴和非侵入式血糖估算
Yiting Wei,Bingo Wing-Kuen Ling,Danni Chen et al.
Yiting Wei et al.
The traditional blood glucose estimation method requires to take the invasive measurements several times a day. Therefore, it has a high infection risk and the users are suffered from the pain. Moreover, the long term consumable cost is hig...
Identification of key immune-related genes and immune infiltration in diabetic nephropathy based on machine learning algorithms [0.03%]
基于机器学习算法识别糖尿病肾病中关键免疫相关基因及免疫浸润
Yue Sun,Weiran Dai,Wenwen He
Yue Sun
Background: Diabetic nephropathy (DN) is a complication of diabetes. This study aimed to identify potential diagnostic markers of DN and explore the significance of immune cell infiltration in this pathology. ...
In silico analysis of the association between long non-coding RNA family with sequence similarity 99 member A (FAM99A) and hepatic cancer [0.03%]
长非编码RNA家族同源成员A(FAM99A)与肝癌关联的计算机分析
Manyi Sun,Shuhua Lv,Jin Zhong
Manyi Sun
The link between family with sequence similarity 99 member A (FAM99A), a type of long non-coding RNA, and tumourigenesis remains ambiguous. Therefore, in this study, the authors conducted an expression profile analysis of FAM99A based on 33...
Down-regulation and clinical significance of Sorbin and SH3 domain-containing protein 1 in bladder cancer tissues [0.03%]
Sorbin和SH3域含有蛋白1在膀胱癌组织中的下调及其临床意义
Sheng-Hua Li,Gao-Qiang Zhai,Rong-Quan He et al.
Sheng-Hua Li et al.
Bladder cancer (BC) is a common cancer worldwide with a high prevalence. This study was conducted to elucidate the expression and clinical significance of Sorbin and SH3 domain-containing protein 1 (SORBS1) in BC as well as to explore its m...