Developing a machine learning model with enhanced performance for predicting COVID-19 from patients presenting to the emergency room with acute respiratory symptoms [0.03%]
一种预测急诊急性呼吸道症状患者感染新冠肺炎的高性能机器学习模型及其研发
Maha Mesfer Alghamdi,Naael H Alazwary,Waleed A Alsowayan et al.
Maha Mesfer Alghamdi et al.
Artificial Intelligence is playing a crucial role in healthcare by enhancing decision-making and data analysis, particularly during the COVID-19 pandemic. This virus affects individuals across all age groups, but its impact is more severe o...
Mechanism of action of "cistanche deserticola-Polygala" in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis [0.03%]
基于网络药理学方法及分子对接分析的“肉苁蓉远志”对阿尔茨海默病作用机制研究
Shaoqiang Wang,Yifan Wang
Shaoqiang Wang
This article used network pharmacology, molecular docking, GEO analysis, and Gene Set Enrichment Analysis to obtain 38 main chemical components and 66 corresponding targets involved in Alzheimer's disease (AD) treatment in "Cistanche desert...
Comprehensive transcriptome and scRNA-seq analyses uncover the expression and underlying mechanism of SYNJ2 in papillary thyroid carcinoma [0.03%]
全面的转录组和单细胞 RNA 测序分析揭示了 SYNJ2 在乳头状甲状腺癌中的表达及潜在作用机制
Yuan-Ping Yang,Zhi-Guang Huang,Jia-Yuan Luo et al.
Yuan-Ping Yang et al.
Synaptojanin 2 (SYNJ2) has crucial role in various tumors, but its role in papillary thyroid carcinoma (PTC) remains unexplored. This study first detected SYNJ2 protein expression in PTC using immunohistochemistry method and further assesse...
iGATTLDA: Integrative graph attention and transformer-based model for predicting lncRNA-Disease associations [0.03%]
基于整合图注意力和变换器的lnrnadisease关联预测模型_iGattLda
Biffon Manyura Momanyi,Sebu Aboma Temesgen,Tian-Yu Wang et al.
Biffon Manyura Momanyi et al.
Long non-coding RNAs (lncRNAs) have emerged as significant contributors to the regulation of various biological processes, and their dysregulation has been linked to a variety of human disorders. Accurate prediction of potential correlation...
A tumour-associated macrophage-based signature for deciphering prognosis and immunotherapy response in prostate cancer [0.03%]
基于肿瘤相关巨噬细胞的预后及免疫治疗反应解码前列腺癌标志物
Jian Wang,Tao Guo,Yuanyuan Mi et al.
Jian Wang et al.
For the multistage progression of prostate cancer (PCa) and resistance to immunotherapy, tumour-associated macrophage is an essential contributor. Although immunotherapy is an important and promising treatment modality for cancer, most pati...
Identification and analysis of epithelial-mesenchymal transition-related key long non-coding RNAs in hypospadias [0.03%]
低氧诱导因子-1α相关长链非编码RNA在慢性髓性白血病中的表达及意义研究
Hongjie Gao,Chen Ding,Mengmeng Chang et al.
Hongjie Gao et al.
EMT dysfunction is a dominant mechanisms of hypospadias. Thus, identification of EMT-related lncRNAs based on transcriptome sequencing data of hypospadias might provide novel molecular markers and therapeutic targets for hypospadias. First,...
Revealing the potential role of hub metabolism-related genes and their correlation with immune cells in acute ischemic stroke [0.03%]
揭示急性缺血性卒中中心理代谢相关基因的潜在作用及其与免疫细胞的相关性
Xianjing Zhang,Tengxiao Xu,Chen Wang et al.
Xianjing Zhang et al.
Objectives: Acute ischemic stroke (AIS) is caused by cerebral ischemia due to thrombosis in the blood vessel. The purpose of this study is to identify key genes related to metabolism to aid in the mechanism research and m...
Gene signatures of endoplasmic reticulum stress and mitophagy for prognostic risk prediction in lung adenocarcinoma [0.03%]
肺腺癌中内质网应激和线粒体自噬的基因标志物用于预后风险预测
Xiong Lin,Miaoling Yang,Yuanling Huang et al.
Xiong Lin et al.
Genes associated with endoplasmic reticulum stress (ERS) and mitophagy can be conducive to predicting solid tumour prognosis. The authors aimed to develop a prognosis prediction model for these genes in lung adenocarcinoma (LUAD). Relevant ...
Adjusting laser power to control the heat generated by nanoparticles at the site of a patient's cells [0.03%]
调节激光功率以控制纳米颗粒在患者细胞部位产生的热量
Seyed Ehsan Razavi,Hamed Khodadadi,Masoud Goharimanesh
Seyed Ehsan Razavi
Cancer treatment often involves heat therapy, commonly administered alongside chemotherapy and radiation therapy. The authors address the challenges posed by heat treatment methods and introduce effective control techniques. These approache...
DNA methylation plays important roles in lifestyle transition of Arthrobotrys oligospora [0.03%]
DNA甲基化在粘帚霉生活方式转换中起重要作用
Jiajia Shi,Jiaxin Liu,Heng Li et al.
Jiajia Shi et al.
Trap formation is the key indicator of carnivorous lifestyle transition of nematode-trapping fungi (NTF). Here, the DNA methylation profile was explored during trap induction of Arthrobotrys oligospora, a typical NTF that captures nematodes...