Dhruba Jyoti Bora,Rajdeep Dasgupta
Dhruba Jyoti Bora
Transdermal drug delivery is a non-invasive method of drug administration. However, to achieve this, the drug has to pass through the complicated structure of the skin. The complex structure of skin can be modelled by an electrical equivale...
Blood glucose regulation and control of insulin and glucagon infusion using single model predictive control for type 1 diabetes mellitus [0.03%]
单模型预测控制调节I型糖尿病血糖及胰岛素和胰高糖素的输注
Cifha Crecil Dias,Surekha Kamath,Sudha Vidyasagar
Cifha Crecil Dias
This study elaborates on the design of artificial pancreas using model predictive control algorithm for a comprehensive physiological model such as the Sorensen model, which regulates the blood glucose and can have a longer control time in ...
Soumyadip Banerjee,Shaunak Sen
Soumyadip Banerjee
Biomolecular oscillators can function robustly in the presence of environmental perturbations, which can either be static or dynamic. While the effect of different circuit parameters and mechanisms on the robustness to steady perturbations ...
Identification of specific microRNA-messenger RNA regulation pairs in four subtypes of breast cancer [0.03%]
四种亚型乳腺癌中特定microRNA-信使RNA调控对的鉴定
Ling Guo,Aihua Zhang,Jie Xiong
Ling Guo
Four subtypes of breast cancer, luminal A, luminal B, basal-like, human epidermal growth factor receptor-enriched, have been identified based on gene expression profiles of human tumours. The goal of this study is to find whether the same g...
Application of conditional robust calibration to ordinary differential equations models in computational systems biology: a comparison of two sampling strategies [0.03%]
条件稳健校准在计算系统生物学中的应用:两种抽样策略的比较
Fortunato Bianconi,Chiara Antonini,Lorenzo Tomassoni et al.
Fortunato Bianconi et al.
Mathematical modelling is a widely used technique for describing the temporal behaviour of biological systems. One of the most challenging topics in computational systems biology is the calibration of non-linear models; i.e. the estimation ...
Comparative Study
IET systems biology. 2020 Jun;14(3):107-119. DOI:10.1049/iet-syb.2018.5091 2020
Coupling of cell fate selection model enhances DNA damage response and may underlie BE phenomenon [0.03%]
细胞命运选择模型耦合增强DNA损伤修复可能解释了 Barrett食管现象的原因
Gökhan Demirkıran,Güleser Kalaycı Demir,Cüneyt Güzeliş
Gökhan Demirkıran
Double-strand break-induced (DSB) cells send signal that induces DSBs in neighbour cells, resulting in the interaction among cells sharing the same medium. Since p53 network gives oscillatory response to DSBs, such interaction among cells c...
Chaotic emperor penguin optimised extreme learning machine for microarray cancer classification [0.03%]
基于混沌皇帝企鹅优化极性机器的微阵列癌症分类方法研究
Santos Kumar Baliarsingh,Swati Vipsita
Santos Kumar Baliarsingh
Microarray technology plays a significant role in cancer classification, where a large number of genes and samples are simultaneously analysed. For the efficient analysis of the microarray data, there is a great demand for the development o...
Network-based computational approach to identify genetic links between cardiomyopathy and its risk factors [0.03%]
基于网络的计算方法识别心肌病及其风险因素之间的遗传联系
Md Nasim Haidar,M Babul Islam,Utpala Nanda Chowdhury et al.
Md Nasim Haidar et al.
Cardiomyopathy (CMP) is a group of myocardial diseases that progressively impair cardiac function. The mechanisms underlying CMP development are poorly understood, but lifestyle factors are clearly implicated as risk factors. This study aim...
Abhishek Dey,Venkat Bokka,Shaunak Sen
Abhishek Dey
Temperature is an important determinant of bacterial growth. While the dependence of bacterial growth on different temperatures has been well studied for many bacterial species, prediction of bacterial growth rate for dynamic temperature ch...
Hypnosis regulation in propofol anaesthesia employing super-twisting sliding mode control to compensate variability dynamics [0.03%]
应用超强扭转滑模控制的异丙酚麻醉中超催眠效应的补偿变异动力学调节
Muhammad Ilyas,Jamshed Iqbal,Sayyar Ahmad et al.
Muhammad Ilyas et al.
Regulation of hypnosis level on bi-spectral index monitor (BIS) during a surgical procedure in propofol anaesthesia administration is a challenging task for an anaesthesiologist in multi-tasking environment of the operation theater. Automat...