Anuj Deshpande,Sibendu Samanta,Sutharsan Govindarajan et al.
Anuj Deshpande et al.
Dynamic biological systems can be modelled to an equivalent modular structure using Boolean networks (BNs) due to their simple construction and relative ease of integration. The chemotaxis network of the bacterium Escherichia coli (E. coli)...
Using sliding mode observers to estimate BtuB concentration from measured vitamin B12 concentration [0.03%]
利用滑模观测器从维生素B12浓度测量值中估算BtuB浓度
Mohammad Abbadi,Sarah Spurgeon,Martin Warren et al.
Mohammad Abbadi et al.
A simple model for the B12-riboswitch regulatory network in Escherichia coli is first described and the same analysis is applied when changing the strain to Salmonella enterica. Model validation is undertaken by linking the dynamics of the ...
TriRNSC: triclustering of gene expression microarray data using restricted neighbourhood search [0.03%]
基于限制邻域搜索的基因表达数据三聚类算法
Bhawani Sankar Biswal,Sabyasachi Patra,Anjali Mohapatra et al.
Bhawani Sankar Biswal et al.
Computational analysis of microarray data is crucial for understanding the gene behaviours and deriving meaningful results. Clustering and biclustering of gene expression microarray data in the unsupervised domain are extremely important as...
Prognostic alternative splicing signature in cervical squamous cell carcinoma [0.03%]
宫颈鳞癌的预后可替代剪切标志物
Hua-Yu Wu,Qi-Qi Li,Liang Liang et al.
Hua-Yu Wu et al.
Basing on alternative splicing events (ASEs) databases, the authors herein aim to explore potential prognostic biomarkers for cervical squamous cell carcinoma (CESC). mRNA expression profiles and relevant clinical data of 223 patients with ...
Arbitrary-order sliding mode-based robust control algorithm for the developing artificial pancreas mechanism [0.03%]
基于任意阶滑模理论的人工胰岛素机制的鲁棒控制算法研究
Waqar Alam,Qudrat Khan,Raja Ali Riaz et al.
Waqar Alam et al.
In Diabetes Mellitus, the pancreas remains incapable of insulin administration that leads to hyperglycaemia, an escalated glycaemic concentration, which may stimulate many complications. To circumvent this situation, a closed-loop control s...
Bifurcation and oscillatory dynamics of delayed CDK1-APC feedback loop [0.03%]
含有延迟的CDK1-APC反馈环的分支和振荡动力学研究
Shenshuang Zhou,Wei Zhang,Yuan Zhang et al.
Shenshuang Zhou et al.
Extensive experimental evidence has been demonstrated that the dynamics of CDK1-APC feedback loop play crucial roles in regulating cell cycle processes, but the dynamical mechanisms underlying the regulation of this loop are still not compl...
Identification of robust genes in transcriptional regulatory network of Mycobacterium tuberculosis [0.03%]
结核分枝杆菌转录调控网络中稳健基因的识别
Prithvi Singh,Mohd Amir,Upasana Chaudhary et al.
Prithvi Singh et al.
About 30% of the world population is infected with Mycobacterium tuberculosis (MTB). It is well known that the gene expression in MTB is highly variable, thus screening of traditional single-gene in MTB has been incapable to meet the desire...
Combinatorial dynamics of protein synthesis time delay and negative feedback loop in NF- κ B signalling pathway [0.03%]
NF-κB信号通路中蛋白质合成时间延迟与负反馈环的组合动力学研究
Fang Yan,Li Liu,Qingyun Wang
Fang Yan
The transcription factor NF-κB links immune response and inflammatory reaction and its different oscillation patterns determine different cell fates. In this study, a mathematical model with IκBα protein synthesis time delay is developed...
Formal reasoning about synthetic biology using higher-order-logic theorem proving [0.03%]
使用高阶逻辑定理证明对合成生物学进行形式化推理
Sa&#x;ed Abed,Adnan Rashid,Osman Hasan
Sa&#x;ed Abed
Synthetic biology is an interdisciplinary field that uses well-established engineering principles for performing the analysis of the biological systems, such as biological circuits, pathways, controllers and enzymes. Conventionally, the ana...
Mostafa Nazari,Morteza Nazari,Mohammad Hadi Noori Skandari
Mostafa Nazari
A mixed chemotherapy-immunotherapy treatment protocol is developed for cancer treatment. Chemotherapy pushes the trajectory of the system towards the desired equilibrium point, and then immunotherapy alters the dynamics of the system by aff...