Optimal neuro-fuzzy control of hepatitis C virus integrated by genetic algorithm [0.03%]
遗传算法优化的神经模糊控制在丙型肝炎病毒中的应用研究
Javad Khodaei-Mehr,Samaneh Tangestanizadeh,Ramin Vatankhah et al.
Javad Khodaei-Mehr et al.
Hepatitis C blood born virus is a major cause of liver disease that more than three per cent of people in the world is dealing with, and the spread of hepatitis C virus (HCV) infection in different populations is one of the most important i...
Effective implicit finite-difference method for sensitivity analysis of stiff stochastic discrete biochemical systems [0.03%]
求解生化系统的灵敏度分析的隐式差分方法
Monjur Morshed,Brian Ingalls,Silvana Ilie
Monjur Morshed
Simulation of cellular processes is achieved through a range of mathematical modelling approaches. Deterministic differential equation models are a commonly used first strategy. However, because many biochemical processes are inherently pro...
Gene expression feature selection for prostate cancer diagnosis using a two-phase heuristic-deterministic search strategy [0.03%]
基于两阶段启发式-确定性搜索策略的选择前列腺癌诊断基因表达特征的研究
Saleh Shahbeig,Akbar Rahideh,Mohammad Sadegh Helfroush et al.
Saleh Shahbeig et al.
Here, a two-phase search strategy is proposed to identify the biomarkers in gene expression data set for the prostate cancer diagnosis. A statistical filtering method is initially employed to remove the noisiest data. In the first phase of ...
Observer-based resilient finite-time control of blood gases model during extra-corporeal circulation [0.03%]
体外循环下基于观测器的血液气体模型有限时间弹性控制
Rathinasamy Sakthivel,Maya Joby,Ohmin Kwon
Rathinasamy Sakthivel
This study aims at designing an observer-based resilient controller to regulate the amount of oxygen and carbon dioxide in the blood of patients during the extra-corporeal blood circulation process. More precisely, in this study, a suitable...
Optimal sliding mode control of drug delivery in cancerous tumour chemotherapy considering the obesity effects [0.03%]
考虑肥胖影响的肿瘤化疗中最佳滑模控制药物输运方法研究
Pariya Khalili,Ramin Vatankhah,Sajjad Taghvaei
Pariya Khalili
Different control strategies have been proposed for drug delivery in chemotherapy during recent years. These control algorithms are designed based on dynamic models of various orders. The order of the model depends on the number of effects ...
Hybrid CME-ODE method for efficient simulation of the galactose switch in yeast [0.03%]
用于高效模拟酵母半乳糖开关的混合CME-ODE方法
David M Bianchi,Joseph R Peterson,Tyler M Earnest et al.
David M Bianchi et al.
It is well known that stochasticity in gene expression is an important source of noise that can have profound effects on the fate of a living cell. In the galactose genetic switch in yeast, the unbinding of a transcription repressor is indu...
Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics [0.03%]
用于p53动力学的二维多项式规范弛豫振子模型
Gökhan Demirkıran,Güleser Kalaycı Demir,Cüneyt Güzeliş
Gökhan Demirkıran
p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle arrest and apopto...
Venkat Bokka,Abhishek Dey,Shaunak Sen
Venkat Bokka
The period and amplitude of biomolecular oscillators are functionally important properties in multiple contexts. For a biomolecular oscillator, the overall constraints in how tuning of amplitude affects period, and vice versa, are generally...
Effect of external periodic signals and electromagnetic radiation on autaptic regulation of neuronal firing [0.03%]
外部周期信号和电磁辐射对自突触神经元放电调节的影响
Mengyan Ge,Ying Xu,Lulu Lu et al.
Mengyan Ge et al.
An improved Hindmarsh-Rose (HR) neuron model, where the memristor is a bridge between membrane potential and magnetic flux, can be used to investigate the effect of periodic signals on autaptic regulation of neurons under electromagnetic ra...
Algorithm to identify the optimal perturbation based on the net basin-of-state of perturbed states in Boolean network [0.03%]
基于布尔网络扰动状态的净盆地状态识别最优摄动的算法
Liangzhong Shen,Xiangzhen Zan,Wenbin Liu
Liangzhong Shen
Boolean networks are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long-term behavior of systems. Here, the authors investigate the 1 bit perturbation, which falls under the ca...