Effects of noise and time delay on E2F's expression level in a bistable Rb-E2F gene's regulatory network [0.03%]
噪声和时间延迟对Rb-E2F双稳态基因调控网络中E2F表达水平的影响分析
John Billy Kirunda,Lijian Yang,Lulu Lu et al.
John Billy Kirunda et al.
The bistable Rb-E2F gene regulatory network plays a central role in regulating cellular proliferation-quiescence transition. Based on Gillespie's chemical Langevin method, the stochastic bistable Rb-E2F gene's regulatory network with time d...
Weighted gene co expression network analysis (WGCNA) with key pathways and hub-genes related to micro RNAs in ischemic stroke [0.03%]
缺血性卒中的加权基因共表达网络分析(WGCNA)及其关键通路和核心基因(与微小RNA相关)
Xiang Qu,Shuang Wu,Jinggui Gao et al.
Xiang Qu et al.
Ischemic stroke (IS) is one of the major causes of death and disability worldwide. However, the specific mechanism of gene interplay and the biological function in IS are not clear. Therefore, more research into IS is necessary. Dataset GSE...
Bifurcation analyses and potential landscapes of a cortex-basal ganglia-thalamus model [0.03%]
皮层-纹状体-丘脑模型的分岔分析及其势能景观研究
Chenri Yan,Quansheng Liu,Yuanhong Bi
Chenri Yan
The dynamics of cortical neuronal activity plays important roles in controlling body movement and is regulated by connection weights between neurons in a cortex-basal ganglia-thalamus (BGCT) loop. Beta-band oscillation of cortical activity ...
State Feedback and Synergetic controllers for tuberculosis in infected population [0.03%]
受感染人群中结核病的状反馈和协同控制器
Muhammad Bilal,Iftikhar Ahmad,Sheraz Ahmad Babar et al.
Muhammad Bilal et al.
Tuberculosis (TB) is a contagious disease which can easily be disseminated in a society. A five state Susceptible, exposed, infected, recovered and resistant (SEIRs) epidemiological mathematical model of TB has been considered along with tw...
Sliding-mode-based controllers for automation of blood glucose concentration for type 1 diabetes [0.03%]
基于滑模的控制器在1型糖尿病血糖浓度自动控制中的应用
Sheraz Ahmad Babar,Iftikhar Ahmad,Iqra Shafeeq Mughal
Sheraz Ahmad Babar
Destruction of β-cells in pancreas causes deficiency in insulin production that leads to diabetes in the human body. To cope with this problem, insulin is either taken orally during the day or injected into the patient's body using artific...
Fuzzy logic and Lyapunov-based non-linear controllers for HCV infection [0.03%]
基于模糊逻辑和李雅普诺夫的非线性控制器在HCV感染中的应用
Ali Hamza,Iftikhar Ahmad,Muhammad Uneeb
Ali Hamza
Hepatitis C is the liver disease caused by the Hepatitis C virus (HCV) which can lead to serious health problems such as liver cancer. In this research work, the non-linear model of HCV having three state variables (uninfected hepatocytes, ...
Identifying the degree of genetic interactions using Restricted Boltzmann Machine-A study on colorectal cancer [0.03%]
基于限制玻尔兹曼机的基因遗传互作效应检测研究——以结直肠癌数据为例
Sujay Saha,Saikat Bandopadhyay,Anupam Ghosh
Sujay Saha
The phenomenon of two or more genes affecting the expression of each other in various ways in the development of a single character of an organism is known as gene interaction. Gene interaction not only applies to normal human traits but to...
Model predictive control optimisation using the metaheuristic optimisation for blood pressure control [0.03%]
基于元启发式优化的模型预测控制在血压控制中的应用
Mohammad Reza Ahmadpour,Hamid Ghadiri,Saeed Reza Hajian
Mohammad Reza Ahmadpour
Given the importance of high blood pressure, it is important to control and maintain a constant blood pressure level in the normal state. The main aim of this article is to design a model predictive controller with a genetic algorithm (GA) ...
MiRNA-145-5p expression and prospective molecular mechanisms in the metastasis of prostate cancer [0.03%]
微小核糖核酸-145-5p在前列腺癌转移中的表达及其潜在分子机制研究
Zhi-Guang Huang,Yu Sun,Gang Chen et al.
Zhi-Guang Huang et al.
The clinicopathological implication and prospective molecular mechanisms of miRNA-145-5p in the metastasis of prostate cancer (PCa) stand unclear. Herein, it is found that miRNA-145-5p expression was remarkably reduced in 131 cases of metas...
Optimal control methods for drug delivery in cancerous tumour by anti-angiogenic therapy and chemotherapy [0.03%]
抗血管生成疗法和化疗的肿瘤药物传递的最佳控制方法研究
Pariya Khalili,Sareh Zolatash,Ramin Vatankhah et al.
Pariya Khalili et al.
There are numerous mathematical models simulating the behaviour of cancer by considering variety of states in different treatment strategies, such as chemotherapy. Among the models, one is developed which is able to consider the blood vesse...