The microbial terroir: open questions on the Nagoya protocol applied to microbial resources [0.03%]
名古屋协议应用于微生物资源的若干问题探讨
Javier Pascual,Kristie Tanner,Cristina Vilanova et al.
Javier Pascual et al.
The Nagoya Protocol on Access and Benefit-sharing (https://www.cbd.int/abs/), primarily designed for vascular plant and animal resources, is also extended to the use of microbial resources, but its application to the microbiological realm h...
Depolymerization of biorefinery lignin by improved laccases of the white-rot fungus Obba rivulosa [0.03%]
一种白色腐朽真菌Obba rivulosa的改良型漆酶对生物精炼 lignin 的降解作用
Janne Wallenius,Jussi Kontro,Christina Lyra et al.
Janne Wallenius et al.
Fungal laccases are attracting enzymes for sustainable valorization of biorefinery lignins. To improve the lignin oxidation capacity of two previously characterized laccase isoenzymes from the white-rot fungus Obba rivulosa, we mutated thei...
Combination of an engineered Lactococcus lactis expressing CXCL12 with light-emitting diode yellow light as a treatment for scalded skin in mice [0.03%]
工程菌乳酸乳球菌表达CXCL12结合发光二极管黄光治疗小鼠烫伤皮肤的效果研究
Xiaoxiao Zhao,Shengjie Li,Jianing Ding et al.
Xiaoxiao Zhao et al.
Impaired wound closure is an increasingly crucial clinical challenge. Recently, wound healing has shifted towards innovative treatments that exploit nanotechnology, biomaterials, biologics and phototherapy. Here, we constructed an engineere...
Enhanced production of neoagarobiose from agar with Corynebacterium glutamicum producing exo-type and endo-type β-agarases [0.03%]
产生外切和内切β-琼胶酶的棒状杆菌增强生产新琼代糖的研究
Eun Jung Jeon,Jae Woong Choi,Min Soo Cho et al.
Eun Jung Jeon et al.
Neoagarobiose (NA2) derived from agar marine biomass is a rare reagent that acts as an anti-melanogenesis reagent and moisturizer. Here, for the economical manufacturing of NA2, we developed the co-secretory production system of endo-type ...
Metabolic engineering of Escherichia coli for biosynthesis of β-nicotinamide mononucleotide from nicotinamide [0.03%]
利用代谢工程由烟酰胺产生β-烟酸单核苷酸的工程大肠杆菌的构建与鉴定
Yang Liu,Montri Yasawong,Bo Yu
Yang Liu
The β-nicotinamide mononucleotide (NMN) is a key intermediate of an essential coenzyme for cellular redox reactions, NAD. Administration of NMN is reported to improve various symptoms, such as diabetes and age-related physiological decline...
Enhancement of edeine production in Brevibacillus brevis X23 via in situ promoter engineering [0.03%]
通过原位启动子工程技术提高短小芽孢杆菌X23中埃德因的产量
Qingshu Liu,Liang Zhang,Yunsheng Wang et al.
Qingshu Liu et al.
Edeines, a group of cationic antimicrobial peptides produced by the soil bacterium Brevibacillus, have broad biological effects, such as antimicrobial, anticancer and immunosuppressive activities. However, the yield of edeines in wild-type ...
A newly developed PCR-based method revealed distinct Fusobacterium nucleatum subspecies infection patterns in colorectal cancer [0.03%]
一种新开发的基于PCR的方法揭示了牙周病细菌核梭杆菌不同亚种在结直肠癌中的感染模式
Dexi Bi,Yin Zhu,Yaohui Gao et al.
Dexi Bi et al.
Fusobacterium nucleatum, which has four subspecies (nucleatum, animalis, vincentii and polymorphum), plays an important role in promoting colorectal cancer (CRC). However, as there is no efficient method of differentiating these subspecies ...
Enhanced bioproduction of anticancer precursor vindoline by yeast cell factories [0.03%]
通过酵母细胞工厂增强抗肿瘤前体长春西丁的生物生产
Natalja Kulagina,Grégory Guirimand,Céline Melin et al.
Natalja Kulagina et al.
The pharmaceutical industry faces a growing demand and recurrent shortages in many anticancer plant drugs given their extensive use in human chemotherapy. Efficient alternative strategies of supply of these natural products such as bioprodu...
Functional dissection and modulation of the BirA protein for improved autotrophic growth of gas-fermenting Clostridium ljungdahlii [0.03%]
功能性分解和调节巴氏芽孢杆菌蛋白质以提高产乙醇梭菌的自养生长率
Can Zhang,Xiaoqun Nie,Huan Zhang et al.
Can Zhang et al.
Gas-fermenting Clostridium species can convert one-carbon gases (CO2 /CO) into a variety of chemicals and fuels, showing excellent application prospects in green biological manufacturing. The discovery of crucial genes and proteins with nov...