Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation [0.03%]
乙酸通过JAK1/STAT3介导的M1巨噬细胞极化缓解子宫内膜异位症
Yunyun Xu,Yichen Zhu,Xiaoyun Wu et al.
Yunyun Xu et al.
Endometriosis (EMs) is a common inflammatory disorder in women of reproductive age, severely impacting patients' quality of life and fertility. Current hormonal therapies offer limited efficacy, and surgical interventions often fail to prev...
Dual Role of MtHAC-1 in Regulating Cellulase and Xylanase Production in Myceliophthora thermophila [0.03%]
MtHAC-1调控链霉菌产纤维素酶和木聚糖酶的正负调控作用研究
Yapeng Lai,Juan Wang,Ning Xie et al.
Yapeng Lai et al.
Filamentous fungi produce large quantities of cellulase and xylanase as extracellular enzymes to degrade plant-derived polysaccharides. This process is controlled by a complex network of transcription factors (TFs). Here, we present the bZI...
Comparative Genomic Assessment of the Cupriavidus necator Species for One-Carbon Based Biomanufacturing [0.03%]
铜矿小单胞菌物种的比较基因组评估及其在基于一碳生物制造中的应用
Magnus G Jespersen,Emil Funk Vangsgaard,Mariana Arango Saavedra et al.
Magnus G Jespersen et al.
The transition from a petroleum-based manufacturing to biomanufacturing is an important step towards a sustainable bio-economy. In particular, biotechnological processes which use one carbon (C1) compounds as feedstock represent an interest...
Lyophilised Reverse Transcriptase and Polymerase for Point-of-Care Diagnostics of SARS-CoV-2 [0.03%]
用于SARS-CoV-2即时诊断的冻干逆转录酶和聚合酶
Natalie Mutter,Barbara Posch,Yasmin Gillitschka et al.
Natalie Mutter et al.
Early diagnosis of pathogens is key to reducing their spreading and to preventing severe health risks. The COVID-19 pandemic showed us the need for rapid point-of-care tests. Here, we describe the preparation of an amplification master mix ...
Synergy of ATP and Meropenem in Stimulating the TCA Cycle to Enhance Killing of Carbapenem-Resistant Acinetobacter baumannii [0.03%]
ATP和美罗培南协同作用刺激碳青霉烯耐药鲍曼不动杆菌三羧酸循环以增强杀菌效应
Xia Li,Dingyun Feng,Jianxia Zhou et al.
Xia Li et al.
The global prevalence of carbapenem-resistant Acinetobacter baumannii (CRAB) represents a substantial concern for public health. Exogenous adenosine triphosphate (ATP) affects the bactericidal efficacy of meropenem against CRAB; however, th...
Rachel Armstrong
Rachel Armstrong
This opinion piece proposes that the environmental crises of our time arise from a failure to recognise the vital role of microbes in sustaining life on Earth, where ecosystems have been shaped for billions of years by microbial processes, ...
Microbial Biotechnology as a Catalyst for a Better and More Sustainable World [0.03%]
微生物技术——创造更美好的可持续世界的重要催化剂
Carmen Michán,Juan L Ramos
Carmen Michán
Education is our most powerful tool for transforming society and improving human well-being. Microbial Biotechnology has previously addressed how we can contribute to enhance public understanding of microbiology in general, and microbial bi...
Artificial Endosymbiosis of Pedobacter sp. DDGJ Boosts the Growth Potential, Stress Resistance and Productivity of Morchella Mushrooms [0.03%]
芽孢杆菌的人工内共生促进马勃菌的生长潜力、胁迫抗性和生产力增强作用研究
Wenchang Zhang,Mantang Cao,Qi Yin et al.
Wenchang Zhang et al.
True morels are precious edible and medicinal mushrooms. The sustainable development of morel cultivation necessitates urgent breeding programmes to develop improved varieties or strains. Some soil bacteria, including Pedobacter spp., are r...
Phage-Antibiotic Combinations for Pseudomonas: Successes in the Clinic and In Vitro Tenuously Connected [0.03%]
噬菌体-抗生素结合物用于铜绿假单胞菌：临床和体外的有限联系
Rabia Fatima,Alexander P Hynes
Rabia Fatima
Antimicrobial resistance challenges researchers to innovate strategies to enhance the effectiveness of our existing antibiotics. Bacteriophage (phage, bacterial virus)-antibiotic combinations present a promising synergistic approach, partic...
A Novel Metallo-β-Lactamase AMM-1 From Alteromonas mangrovi Reveals a Cryptic Environmental Reservoir of Carbapenem Resistance [0.03%]
来源于盐单胞菌的新颖金属β-内酰胺酶AMM-1揭示了碳青霉烯耐药性的隐秘环境库
Xuan Wu,Xinjing Han,Lu Zhu et al.
Xuan Wu et al.
Carbapenem resistance driven by metallo-β-lactamases (MBLs) poses a formidable global challenge as these enzymes can degrade a wide range of β-lactam antibiotics, including last-line carbapenems. Despite extensive documentation of MBL-pro...