Standardization of regulatory nodes for engineering heterologous gene expression: a feasibility study [0.03%]
异源基因表达调控节点标准化的可行性研究
Pablo I Nikel,Ilaria Benedetti,Nicolas T Wirth et al.
Pablo I Nikel et al.
The potential of LacI/Ptrc , XylS/Pm , AlkS/PalkB , CprK/PDB3 and ChnR/PchnB regulatory nodes, recruited from both Gram-negative and Gram-positive bacteria, as the source of parts for formatting expression cargoes following the Standard Eur...
Enzyme cascade converting cyclohexanol into ε-caprolactone coupled with NADPH recycling using surface displayed alcohol dehydrogenase and cyclohexanone monooxygenase on E. coli [0.03%]
利用大肠杆菌表面展示的酒精脱氢酶和环己酮单加氧酶偶联NADPH循环催化的环己醇到ε-己内酯合成路径研究
Haijin Tian,Christoph Furtmann,Florian Lenz et al.
Haijin Tian et al.
The application of enzymes as biocatalysts in industrial processes has great potential due to their outstanding stereo-, regio- and chemoselectivity. Using autodisplay, enzymes can be immobilized on the cell surface of Gram-negative bacteri...
Identification of VdASP F2-interacting protein as a regulator of microsclerotial formation in Verticillium dahliae [0.03%]
鉴定菌核形成调控因子VdASP-F2相互作用蛋白
Cuimei Guo,Xing Yang,Hongli Shi et al.
Cuimei Guo et al.
Verticillium dahliae, a notorious phytopathogenic fungus, causes vascular wilt diseases in many plant species. The melanized microsclerotia enable V. dahliae to survive for years in soil and are crucial for its disease cycle. In a previous ...
COVID-19: Omicron - the latest, the least virulent, but probably not the last variant of concern of SARS-CoV-2 [0.03%]
新冠肺炎：奥密克戎——最新、致病性最弱，但绝不会是最后一种值得关注的新冠病毒变异毒株
Harald Brüssow
Harald Brüssow
The Omicron variant rapidly became the dominant SARS-CoV-2 strain in South Africa and elsewhere. This review explores whether this rise was due to an increased transmission of the variant or its escape from population immunity by an extensi...
Cepharanthine ameliorates dextran sulphate sodium-induced colitis through modulating gut microbiota [0.03%]
cepharanthine通过调节肠道微生物群改善dextran硫酸钠诱导的结肠炎
Hong-Gang Wang,Min-Na Zhang,Xin Wen et al.
Hong-Gang Wang et al.
Cepharanthine (CEP) is an active alkaloid isolated from Stephania Cepharantha Hayata. It is reported that the anti-inflammatory properties of CEP could be employed to treat a variety of diseases. In this study, we first found that CEP ameli...
Identification of genome integration sites for developing a CRISPR-based gene expression toolkit in Yarrowia lipolytica [0.03%]
在解脂耶氏酵母中鉴定基因组整合位点以开发CRISPR表达工具包
Xiaoqin Liu,Zhiyong Cui,Tianyuan Su et al.
Xiaoqin Liu et al.
With the rapid development of synthetic biology, the oleaginous yeast Yarrowia lipolytica has become an attractive microorganism for chemical production. To better optimize and reroute metabolic pathways, we have expanded the CRISPR-based g...
Colonization of nasal cavities by Staphylococcus epidermidis mitigates SARS-CoV-2 nucleocapsid phosphoprotein-induced interleukin (IL)-6 in the lung [0.03%]
表皮葡萄球菌定植鼻腔可减轻SARS-CoV-2核衣壳磷酸蛋白诱导的肺部白细胞介素(IL)-6过度表达
Ming-Shan Kao,Jen-Ho Yang,Arun Balasubramaniam et al.
Ming-Shan Kao et al.
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can trigger excessive interleukin (IL)-6 signalling, leading to a myriad of biological effects including a cytokine storm that contributes to multiple organ failure i...
Novel protein carrier system based on cyanobacterial nano-sized extracellular vesicles for application in fish [0.03%]
基于鱼藤黄菌纳米级胞外囊泡的新蛋白质递送系统用于鱼类研究
Jorge Matinha-Cardoso,Filipe Coutinho,Steeve Lima et al.
Jorge Matinha-Cardoso et al.
Aquaculture has been one of the fastest-growing food industry sectors, expanding at the pace of consumers' demands. To promote safe and effective fish growth performance strategies, and to stimulate environmentally friendly solutions to pro...
Biofilm formation as an extra gear for Apilactobacillus kunkeei to counter the threat of agrochemicals in honeybee crop [0.03%]
葡萄糖醋杆菌生物被膜的形成增强了蜜蜂肠道对农药胁迫的抵抗能力
Ali Zein Alabiden Tlais,Andrea Polo,Pasquale Filannino et al.
Ali Zein Alabiden Tlais et al.
The alteration of a eubiosis status in honeybees' gut microbiota is directly linked to the occurrence of diseases, and likely to the honeybees decline. Since fructophilic lactobacilli were suggested as symbionts for honeybees, we mechanisti...
Aimee R Harper,Renwick C J Dobson,Vanessa K Morris et al.
Aimee R Harper et al.
Ethical, environmental and health concerns around dairy products are driving a fast-growing industry for plant-based dairy alternatives, but undesirable flavours and textures in available products are limiting their uptake into the mainstre...