Structure-Antimicrobial Activity Relationships of Recombinant Host Defence Peptides Against Drug-Resistant Bacteria [0.03%]
耐药细菌重组宿主防御肽的结构抗菌活性关系研究
Sergi Travé-Asensio,Aida Tort-Miró,Silvana Pinheiro et al.
Sergi Travé-Asensio et al.
Host defence peptides (HDPs) represent a valuable class of antimicrobial agents with the potential to address the growing threat of antimicrobial resistance (AMR). Here, we have studied recombinant constructs based on a combination of HDPs ...
Understanding Bacterial Antiviral Defence Systems and Phage Receptors to Better Inform Rational Phage Cocktail Design to Treat Bacterial Canker [0.03%]
理解细菌抗病毒防御系统和噬菌体受体以更好地理性设计噬菌体鸡尾酒疗法来治疗细菌性溃疡病
Kieran Cooney-Nutley,Sneha Chakravorty,Imogen Nix et al.
Kieran Cooney-Nutley et al.
Pseudomonas syringae is a plant pathogen complex responsible for bacterial canker in cherry. In the absence of any control measures, bacteriophages (phages) have the potential for biocontrol. However, it is crucial to first evaluate the rol...
Anna Łepecka,Danuta Kołożyn-Krajewska
Anna Łepecka
The mechanisms of antioxidant action of lactic acid bacteria (LAB) have not been fully explained. This review aimed to characterise the antioxidant properties that can be presented by LAB strains isolated from food. The review presents a de...
Biotechnological Production, Isolation and Characterisation of (2R,3S)-2,3-Dihydroxy-2,3-Dihydrobenzoate [0.03%]
(2R,3S)-2,3-二羟基-2，3-二氢苯甲酸的生物技术生产、分离与表征
Martina Kiel,Israel Barrantes,Dietmar H Pieper et al.
Martina Kiel et al.
Bacterial Rieske non-heme iron oxygenases catalyse the transformation of a wide range of aromatic compounds to vicinal cis-dihydrodiols. Such compounds have been successfully applied in chemoenzymatic synthetic routes for, for example, phar...
Combinatorial Alkali-Responsive Hybrid Promoters as Tools for Heterologous Protein Expression in Saccharomyces cerevisiae [0.03%]
用于Saccharomyces cerevisiae中异源蛋白质表达的组合型碱金属响应杂合启动子
Abdelghani Zekhnini,Antonio Casamayor,Joaquín Ariño
Abdelghani Zekhnini
The demand for strong and easily inducible promoters to produce heterologous proteins in Saccharomyces cerevisiae has attracted considerable attention in the last years. In this organism, alkalinisation triggers a wide and well-characterise...
Unleashing the Antiviral Potential of Stapled Peptides: A New Frontier in Combating Human Neurotropic Viral Infections [0.03%]
基于环肽的抗人神经源性病毒药物发现与研发的新前沿阵地
Sanskruti Patil,Rakesh Rahangdale,Mukesh Pasupuleti et al.
Sanskruti Patil et al.
Neurotropic viral infections continue to pose significant global health challenges, with pathogens such as herpes simplex virus (HSV), varicella-zoster virus, human immunodeficiency virus, poliovirus, enteroviruses, parechovirus, West Nile ...
Quorum Sensing via Autoinducer-2 Promotes Colonisation and Host Adaptation in B. bifidum PRL2010 [0.03%]
自诱导物-2信号促进婴儿双歧杆菌PRL2010定植及宿主适应性
Francesca Turroni,Chiara Tarracchini,Gabriele Andrea Lugli et al.
Francesca Turroni et al.
Autoinducer-2 (AI-2) is a key signalling molecule that in many bacteria facilitates interspecies communication by regulating gene expression in response to population density through a process known as quorum sensing. While this signalling ...
Boosting Dibenzothiophene Biodesulfurization Through Implantation of a Refactored DBT Pathway in a Tailored Pseudomonas putida Chassis [0.03%]
通过在定制的假单胞菌底盘中植入重构型二苯并噻吩代谢途径来增强二苯并噻吩生物脱硫能力
Panayiotis D Glekas,Ioannis Papageorgopoulos,Stamatios G Damalas et al.
Panayiotis D Glekas et al.
This study reports the efficacy of a rationally designed Pseudomonas putida strain to bring about the specific removal of S atoms from dibenzothiophene (DBT), the model heterocyclic sulfur-containing component of raw petroleum. The emphasis...
Angel J Matilla
Angel J Matilla
The seed microbiota, a still underexplored component of plant-microbe interactions, plays a pivotal role in plant development and holds significant promise for advancing sustainable agriculture. By influencing essential processes such as ge...
A BtpB-Deleted Brucella Vaccine Strain Provides Dual Advantages: Enhanced Protection and Diagnostic Differentiation Capability in Mice [0.03%]
缺失BtpB基因的布鲁氏菌减毒活疫苗株对小鼠具有双重优势：增强免疫保护性及诊断鉴别力
Zhenyu Xu,Xiaoyu Deng,Hengyun Gao et al.
Zhenyu Xu et al.
The Brucella abortus A19 attenuated live vaccine poses potential infection risks during practical applications and interferes with serological diagnostics, thereby affecting quarantine measures and the establishment of disease-free zones. C...