Evolutionary Trajectories of Methionine Metabolism in Mycobacterium and Its Application to Engineer a Vitamin B12 Whole-Cell Ribosensor [0.03%]
甲硫氨酸代谢的进化轨迹及在维生素B12全细胞核糖传感器工程中的应用
Elena Campos-Pardos,Laura Sanz-Asensio,Sandra Pérez-Jiménez et al.
Elena Campos-Pardos et al.
Vitamin B12 metabolism differs among members of the Mycobacterium genus. While non-tuberculous mycobacterial species are B12 producers, tuberculous mycobacteria lack endogenous production and rely on the host supply of this vitamin. Here, w...
Chicken Manure as a Sustainable Bile Acid Source for Biotechnological Applications [0.03%]
鸡粪作为生物技术应用的可持续胆酸来源
Johannes Holert,Rudolf Wilhelm,Jens Henker et al.
Johannes Holert et al.
Ursodeoxycholic acid (UDCA) is widely administered to dissolve gallstones, treat liver disorders and reduce blood cholesterol levels. This study investigated fresh and dried chicken manure as a sustainable bioresource for chenodeoxycholic a...
Exploring Use of a Protein Cage System for Producing Bioactive Peptides in Escherichia coli [0.03%]
探索在大肠杆菌中使用蛋白质笼系统产生活性多肽的方法
Maxim D Harding,Mark A Jackson,Edward K Gilding et al.
Maxim D Harding et al.
New therapeutics are urgently needed to curb the spread of drug-resistant diseases. Bioactive peptides (BAPs), including antimicrobial peptides, are emerging as an exciting new class of compounds with advantages over current drug modalities...
Comparative Colonisation Ability of Human Faecal Microbiome Transplantation Strategies in Murine Models [0.03%]
人粪菌移植在小鼠模型中相对定植能力的比较研究
Bon-Hee Gu,Ho Young Jung,Chae-Yun Rim et al.
Bon-Hee Gu et al.
The gut microbiome plays a crucial role in maintaining intestinal homeostasis and influencing immune-mediated diseases. Human faecal microbiota transplantation (FMT) is often employed in murine models to investigate the role of human microb...
Comparative Study
Microbial biotechnology. 2025 Jun;18(6):e70173. DOI:10.1111/1751-7915.70173 2025
Unlocking Enhanced Efficacy of Aminoglycoside Antibiotics Against Pseudomonas aeruginosa [0.03%]
氨基糖苷类抗生素增强抵御绿脓杆菌的功效研究
Patrick Ofori Tawiah,Sadia Sultana,Jan-Ulrik Dahl
Patrick Ofori Tawiah
Infectious diseases continue to be a global health burden. Among the major human pathogens is the Gram-negative bacterium Pseudomonas aeruginosa, which is particularly due to its wide range of drug resistance mechanisms. Aminoglycosides, wh...
Amino Acids From Root Exudates Induce Bacillus Spore Germination to Enhance Root Colonisation and Plant Growth Promotion [0.03%]
根分泌氨基酸诱导芽孢杆菌孢子萌发以增强其与植物根系的互作及促生效应
Lili Tao,Xinli Sun,Pascale B Beauregard et al.
Lili Tao et al.
Strains of Bacillus species, plant growth-promoting rhizobacteria, have been commercialised as biofertilisers; they are ideal for this because these species form spores that can be stored stably for a long time. However, for these spores to...
Improvement of β-Xylosidase and Endoxylanase Activities in Talaromyces amestolkiae by Genetic Manipulation of the Transcriptional Activator XlnR [0.03%]
通过遗传操纵转录激活子XlnR提高Amestolkia木霉的β-xylosidase和内聚木糖酶活性
Ana Pozo-Rodríguez,Miguel Ángel Peñalva,Jorge Barriuso et al.
Ana Pozo-Rodríguez et al.
The ascomycete Talaromyces amestolkiae is a promising source of glycosyl hydrolases for hemicellulose degradation, as it contains a considerably higher number of genes encoding these enzymes than other fungi exploited for plant biomass valo...
Broad-Spectrum Antimicrobial and Antibiofilm Activities of Halogenated Anilines Against Uropathogenic Escherichia coli and ESKAPE Pathogens [0.03%]
针对泌尿系统病原性大肠杆菌及ESKAPE耐药菌的卤化苯胺类广谱抗菌和抗生物被膜活性研究
Bharath Reddy Boya,Jin-Hyung Lee,Jintae Lee
Bharath Reddy Boya
Uropathogenic Escherichia coli (UPEC) is one of the leading causes of nosocomial infections and urinary tract infections (UTIs), capable of inducing a spectrum of conditions ranging from acute bladder cystitis to chronic pyelonephritis. The...
Xinli Sun,Zhihui Xu,Nan Zhang et al.
Xinli Sun et al.
Reliance on chemical fertilizers has significantly boosted food production in China, but it has also led to soil degradation, environmental pollution, and greenhouse gas emissions. To address these pressing issues, the Chinese government ha...
Production of Vanillin From Ferulic Acid by Pseudomonas putida KT2440 Using Metabolic Engineering and In Situ Product Recovery [0.03%]
利用代谢工程和原位产物回收由类乌金酸通过假单胞菌生产香草醛
Ilona A Ruhl,Sean P Woodworth,Stefan J Haugen et al.
Ilona A Ruhl et al.
Vanillin is the most in-demand flavouring compound in the world and because vanillin extracted from vanilla pods cannot meet the global demand, most vanillin on the market today is chemically synthesised. Increasing demands by consumers for...